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[1]姜聰,王婭,林芝,等.維持性血液透析患者骨質(zhì)疏松影響因素的Meta分析[J].福建醫(yī)藥雜志,2025,47(01):9-13.[doi:10.20148/j.fmj.2025.01.003]
　JIANG Cong,WANG Ya,LIN Zhi,et al.Meta-analysis of influencing factors of osteoporosis in patients with maintenance hemodialysis[J].FUJIAN MEDICAL JOURNAL,2025,47(01):9-13.[doi:10.20148/j.fmj.2025.01.003]
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維持性血液透析患者骨質(zhì)疏松影響因素的Meta分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
47
期數(shù):
2025年01期
頁碼:
9-13
欄目:
臨床研究
出版日期:
2025-01-20

文章信息/Info

Title:
Meta-analysis of influencing factors of osteoporosis in patients with maintenance hemodialysis
文章編號:
1002-2600(2025)01-0009-05
作者:
姜聰1; 王婭1; 林芝1; 穆艷2
1 福建中醫(yī)藥大學(xué)護(hù)理學(xué)院,福州 350122; 2 福建中醫(yī)藥大學(xué)教學(xué)醫(yī)院護(hù)理部(福州大學(xué)附屬省立醫(yī)院護(hù)理部),福州 350001
Author(s):
JIANG Cong1;  WANG Ya1;  LIN Zhi1;  MU Yan2
1 College of Nursing, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122,China; 2 Fujian University of Traditional Chinese Medicine Teaching Hospital(Fuzhou University Affiliated Provincial Hospital), Fuzhou, Fujian 350001,China
關(guān)鍵詞:
終末期腎臟病;  維持性血液透析;  影響因素;  骨質(zhì)疏松;  Meta分析
Keywords:
maintenance hemodialysis;  end-stage renal disease;  influencing factors;  osteoporosis;  meta-analysis
分類號:
R473.5
DOI:
10.20148/j.fmj.2025.01.003
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 對維持性血液透析患者骨質(zhì)疏松的相關(guān)因素進(jìn)行Meta分析。方法 檢索范圍包括PubMed、Embase、Web of Science、Cochrane Library、中國知網(wǎng)、維普、萬方及中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫,檢索時(shí)間范圍為建庫至2024年8月。由兩名研究人員獨(dú)立篩選文獻(xiàn)、提取數(shù)據(jù)并進(jìn)行討論分析,采用RevMan 5.4軟件進(jìn)行Meta分析。結(jié)果 共納入12篇文獻(xiàn)。結(jié)果顯示,女性(OR=3.47,95%CI:2.47,4.88)、透析時(shí)間長(OR=2.84,95%CI:1.71,4.70)、低BMI(OR=2.38,95%CI:1.08,5.25)、高甲狀旁腺素(OR=4.30,95%CI:2.20,8.47)、高齡(OR=1.72,95%CI:1.30,2.28)、患糖尿病(OR=2.94,95%CI:1.80,4.81)、堿性磷酸酶高(OR=3.41,95%CI:1.91,6.09)、絕經(jīng)(OR=7.56,95%CI:2.87,20.36)為骨質(zhì)疏松發(fā)生的危險(xiǎn)因素。結(jié)論 維持性血液透析患者骨質(zhì)疏松的影響因素較多,應(yīng)及早對維持性血液透析患者的骨質(zhì)狀況進(jìn)行干預(yù),降低其不良結(jié)局的發(fā)生率。
Abstract:
Objective To explore the factors associated with osteoporosis outcomes in patients with maintenance hemodialysis through meta-analysis. Methods The search was conducted across PubMed, Embase, Web of Science, Cochrane Library, CNKI, VIP, Wanfang, and CBM databases, covering the period from database inception to August 2024. Two independent researchers screened the literature, extracted the data, and resolved discrepancies through discussion and analysis. Meta-analysis was performed using RevMan 5.4 software. Results A total of 12 literatures were included. The results showed that female gender(OR=3.47,95%CI:2.47,4.88), long duration of dialysis(OR=2.84,95%CI:1.71, 4.70), low BMI(OR=2.38,95%CI:1.08,5.25), high parathyroid hormone(OR=4.30,95%CI:2.20,8.47), advanced age(OR=1.72,95%CI:1.30,2.28), having diabetes mellitus(OR=2.94,95%CI:1.80,4.81), high alkaline phosphatase(OR=3.41,95%CI:1.91,6.09), and menopause(OR=7.56,95%CI:2.87,20.36)were the risk factors for osteoporosis development. Conclusion Various factors can affect osteoporosis in patientswith maintenance hemodialysis,and early interventions should be made to reduce the incidence of adverse outcomes in the bone status of maintenance hemodialysis patients.

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通信作者:穆 艷,Email:[email protected]
更新日期/Last Update: 2025-01-20