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[1]楊燕芬,楊舒萍,林麗卿,等.無創(chuàng)壓力-應(yīng)變環(huán)評估冠心病合并高尿酸血癥患者的心肌做功[J].福建醫(yī)藥雜志,2024,46(03):1-4.[doi:10.20148/j.fmj.2024.03.001]
　YANG Yanfen,YANG Shuping,LIN Liqing,et al.Non-invasive pressure-strain loop assessment of myocardial work in patients with coronary heart disease complicated with hyperuricemia[J].FUJIAN MEDICAL JOURNAL,2024,46(03):1-4.[doi:10.20148/j.fmj.2024.03.001]
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無創(chuàng)壓力-應(yīng)變環(huán)評估冠心病合并高尿酸血癥患者的心肌做功()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
46
期數(shù):
2024年03期
頁碼:
1-4
欄目:
臨床研究
出版日期:
2024-06-15

文章信息/Info

Title:
Non-invasive pressure-strain loop assessment of myocardial work in patients with coronary heart disease complicated with hyperuricemia
文章編號:
1002-2600(2024)03-0001-04
作者:
楊燕芬1; 楊舒萍2; 林麗卿2; 陳榮榮2; 黃淑鉉1; 吳珠娥1; 佘火標2
1 福建醫(yī)科大學臨床醫(yī)學部,福州 350122; 2 福建醫(yī)科大學附屬漳州市醫(yī)院, 漳州 363000
Author(s):
YANG Yanfen1; YANG Shuping2; LIN Liqing2; CHEN Rongrong2; HUANG Shuxuan1; WU Zhue1; SHE Huobiao2
1 School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian 350122, China; 2 Zhangzhou Affiliated Hospital of Fujian Medical Univesity, Zhangzhou, Fujian 363000, China
關(guān)鍵詞:
壓力-應(yīng)變環(huán);  冠心病;  高尿酸血癥;  心肌做功
Keywords:
pressure-strain loop;  coronary artery disease;  hyperuricemia;  myocardial work
分類號:
R445.1; R541.4
DOI:
10.20148/j.fmj.2024.03.001
文獻標志碼:
B
摘要:
目的 應(yīng)用無創(chuàng)壓力-應(yīng)變環(huán)(PSL)評估冠心病合并高尿酸血癥患者的心肌做功情況。方法 回顧性分析2021年12月至2022年12月入住我院心內(nèi)科行數(shù)字減影血管造影(DSA)確診冠心病的119名患者,記錄患者血清尿酸基線水平,根據(jù)血清尿酸水平分為高尿酸組(n=38)和正常尿酸組(n=81),兩組均接受常規(guī)超聲心動圖檢查并應(yīng)用EchoPAC軟件,輸入血壓值構(gòu)建左心室PSL,獲得心肌做功參數(shù),包括整體做功指數(shù)(GWI)、整體有效做功(GCW)、整體無效做功(GWW)、整體做功效率(GWE),GWE=GCW/(GCW+GWW),比較各組上述參數(shù)的差異及與血清尿酸之間的相關(guān)性和回歸性。結(jié)果 兩組的GWI和GCW比較差異均有統(tǒng)計學意義(均P<0.05),高尿酸組的GWI和GCW均減小; Pearson相關(guān)分析表明,GWI、GCW與血尿酸值呈負相關(guān)(r=-0.255、-0.242,P<0.05)。線性回歸分析表明,左室心肌做功值與冠心病患者的血清尿酸值存在線性相關(guān)。結(jié)論 無創(chuàng)壓力-應(yīng)變環(huán)可以量化高尿酸水平對冠心病患者的心肌損害情況,為臨床提供指導價值。
Abstract:
Objective To evaluate myocardial work in patients with coronary heart disease(CHD)complicated with hyperuricemia using non-invasive pressure-strain loops(PSL). Methods A retrospective analysis was conducted on 119 patients with CHD who were admitted to the cardiology department of our hospital and diagnosed with digital subtraction angiography(DSA)from December 2021 to December 2022. The baseline serum uric acid levels of the patients were recorded, and they were divided into a high uric acid group(n=38)and a normal uric acid group(n=81)based on their serum uric acid levels. Both groups underwent routine echocardiography and utilized the EchoPAC software to construct left ventricle PSL by inputting blood pressure values. Myocardial work parameters were obtained, including global work index(GWI), global constructive work(GCW), global wasted work(GWW), and global work efficiency(GWE).GWE=GCW/(GCW+GWW). The differences in these parameters between the groups, as well as their correlation and regression with serum uric acid, were compared. Results There were statistically significant differences in GWI and GCW between the two groups(both P<0.05). Both GWI and GCW were reduced in the high uric acid group. Pearson correlation analysis showed that GWI and GCW were negatively correlated with serum uric acid values(r=-0.255,-0.242,P<0.05). Linear regression analysis showed a linear correlation between left ventricular myocardial work values and serum uric acid levels in patients with CHD. Conclusion Non-invasive pressure-strain loops can quantify the myocardial damage caused by high uric acid levels in patients with CHD, thus providing clinical guidance.

參考文獻/References:

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備注/Memo

備注/Memo:
基金項目:福建省自然科學基金資助項目(2021J011418)
通信作者:佘火標,Email:[email protected]
更新日期/Last Update: 2024-06-15