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[1]莊宸麟,余惠珍陳毓岱,孫嘉峰,等.控制營養(yǎng)狀態(tài)評(píng)分與老年慢性心衰急性發(fā)作患者死亡預(yù)后的相關(guān)性研究[J].福建醫(yī)藥雜志,2023,45(02):16-19.
　ZHUANG Chenlin,YU Huizhen,CHEN Yudai,et al.Study on the correlation between controlling nutritional status score and death prognosis in elderly patients with acute episode of chronic heart failure[J].FUJIAN MEDICAL JOURNAL,2023,45(02):16-19.
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控制營養(yǎng)狀態(tài)評(píng)分與老年慢性心衰急性發(fā)作患者死亡預(yù)后的相關(guān)性研究 ()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
45
期數(shù):
2023年02期
頁碼:
16-19
欄目:
臨床研究
出版日期:
2023-04-15

文章信息/Info

Title:
Study on the correlation between controlling nutritional status score and death prognosis in elderly patients with acute episode of chronic heart failure
文章編號(hào):
1002-2600(2023)02-0016-04
作者:
莊宸麟; 余惠珍1陳毓岱2; 孫嘉峰3; 余鵬1; 陳清1; 朱鵬立4
福建醫(yī)科大學(xué)省立臨床醫(yī)學(xué)院老年醫(yī)學(xué)研究室 福建省立醫(yī)院南院內(nèi)科（福州 350001）
Author(s):
ZHUANG Chenlin;  YU Huizhen;  CHEN Yudai;  SUN Jiafeng;  YU Peng;  CHEN Qing;  ZHU Pengli
Department of Internal Medicine, Fujian Provincial Hospital South Branch, Department of Geriatric Medicine, Provincial Clinical Medical College of Fujian Medical University, Fuzhou, Fujian 350007, China
關(guān)鍵詞:
心力衰竭; 老年; 營養(yǎng)狀況; 預(yù)后; 控制營養(yǎng)狀態(tài)評(píng)分
Keywords:
heart failure;  elderly patients;  nutritional status;  prognosis;  controlling nutritional status score
分類號(hào):
R541.6
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 探究控制營養(yǎng)狀態(tài)（CONUT）評(píng)分與老年慢性心衰（CHF）急性發(fā)作患者死亡預(yù)后的相關(guān)性。方法 連續(xù)性納入年齡≥60歲，因CHF急性發(fā)作在我院住院患者共224例。以全因死亡為終點(diǎn)事件，將隨訪期間發(fā)生死亡的患者歸為死亡組（n=36），余下患者歸為對(duì)照組（n=176）。對(duì)每位患者入院時(shí)進(jìn)行CONUT評(píng)分。采用SPSS 23.0軟件進(jìn)行統(tǒng)計(jì)分析。結(jié)果 死亡組與對(duì)照組相比，體質(zhì)量指數(shù)、心率、淋巴細(xì)胞、血紅蛋白、總蛋白、清蛋白、總膽固醇、估測的腎小球?yàn)V過率降低，CONUT評(píng)分、LogNT-proBNP升高，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。多因素Cox回歸分析顯示，CONUT評(píng)估的營養(yǎng)不良嚴(yán)重程度與死亡事件相關(guān)（P<0.05）。Kaplan-Meier生存曲線顯示，老年CHF急性發(fā)作伴營養(yǎng)不良患者的死亡率高于營養(yǎng)正常狀態(tài)患者，兩者之間差異有統(tǒng)計(jì)學(xué)意義。結(jié)論 營養(yǎng)不良狀態(tài)是老年CHF急性發(fā)作患者遠(yuǎn)期死亡預(yù)后不良的獨(dú)立危險(xiǎn)因素。采用CONUT評(píng)分進(jìn)行營養(yǎng)評(píng)估可較準(zhǔn)確地評(píng)估營養(yǎng)狀況。
Abstract:
Objective To explore the death prognostic value of controlling nutritional status （CONUT） score in elderly patients with acute episode of chronic heart failure were enrolled. Methods A total of 224 elderly patients（age≥60 years） hospitalized for acute episode of chronic heart failure. The primary outcome during follow-up was all-cause mortality. Patients were divided into two groups:death group （n=36） and control group （n=176）. The nutrition stages of patients were evaluated with CONUT. We used software SPSS 23.0 to analyze the basic data. Results The death group had lower body mass index，heart rate，diastolic pressure，lymphocyte, hemoglobin，total protein，albumin，total cholesterol, estimated glomerular filtration rate, compared with control group. However, they had higher CONUT score and LogNT-proBNP （P<0.05）. Multivariate Cox regression analysis showed that malnutrition assessed by CONUT score was an independent risk factor for mortality in elderly patients with acute episode of chronic heart failure（P<0.05）. The Kaplan-Meier survival curve showed that the mortality of malnourished patients was significantly higher than that of non-malnourished patients. Conclusion Malnutrition is independently associated with long-term survival in elderly patients hospitalised with acute episode of chronic heart failure. CONUT can be effective to evaluate the nutritional status.

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備注/Memo

備注/Memo:
1 福建省立醫(yī)院南院內(nèi)科；2 福建省立醫(yī)院南院消化內(nèi)鏡中心；3 福建省立醫(yī)院南院檢驗(yàn)科；4 福建醫(yī)科大學(xué)省立臨床醫(yī)學(xué)院老年醫(yī)學(xué)研究室，通信作者，Email:[email protected]
更新日期/Last Update: 2023-04-15