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[1]趙潔馨,陳彥,許雪峰,等.非酒精性脂肪性肝病與急性胰腺炎嚴(yán)重程度的相關(guān)性分析[J].福建醫(yī)藥雜志,2023,45(01):15-18.
　ZHAO Jiexin,CHEN Yan,XU Xuefeng,et al.Correlation between nonalcoholic fatty liver disease and the severity of acute pancreatitis[J].FUJIAN MEDICAL JOURNAL,2023,45(01):15-18.
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非酒精性脂肪性肝病與急性胰腺炎嚴(yán)重程度的相關(guān)性分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
45
期數(shù):
2023年01期
頁(yè)碼:
15-18
欄目:
臨床研究
出版日期:
2023-02-15

文章信息/Info

Title:
Correlation between nonalcoholic fatty liver disease and the severity of acute pancreatitis
文章編號(hào):
1002-2600(2023)01-0015-04
作者:
趙潔馨; 陳彥1; 許雪峰2; 鄭銘3
福建醫(yī)科大學(xué)省立臨床醫(yī)學(xué)院 福建省立醫(yī)院干部特診二科(福州 350001)
Author(s):
ZHAO Jiexin;  CHEN Yan;  XU Xuefeng;  ZHENG Ming
Department of the second special cadre treatment, Fujian Provincial Hospital, Provincial Clinical Medical College of Fujian Medical University, Fuzhou, Fujian 350001, China
關(guān)鍵詞:
非酒精性脂肪性肝病;  急性胰腺炎;  胰腺炎并發(fā)癥;  獨(dú)立危險(xiǎn)因素
Keywords:
nonalcoholic fatty liver disease;  acute pancreatitis;  complications of pancreatitis;  independent risk factor
分類(lèi)號(hào):
R575.5
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 分析非酒精性脂肪性肝病(NAFLD)與急性胰腺炎(AP)嚴(yán)重程度的相關(guān)性。方法 收集我院AP住院患者331例的臨床資料,按照嚴(yán)重程度分為輕度急性胰腺炎(MAP)、中度重癥急性胰腺炎(MSAP)、重度急性胰腺炎(SAP),進(jìn)行AP嚴(yán)重程度影響因素的多元logistic回歸分析; 將患者分為非NAFLD組與NAFLD組,比較有無(wú)NAFLD與AP嚴(yán)重程度的關(guān)系; 剔除掉非NAFLD組,將NAFLD組按照嚴(yán)重程度分為輕度NAFLD、中度NAFLD、重度NAFLD,對(duì)NAFLD嚴(yán)重程度與AP嚴(yán)重程度進(jìn)行卡方線(xiàn)性趨勢(shì)檢驗(yàn)。結(jié)果 NAFLD是影響AP嚴(yán)重程度的獨(dú)立危險(xiǎn)因素(r=1.177,P<0.05); AP病情隨著NAFLD嚴(yán)重程度而加重(χ2=8.605,P<0.05)。結(jié)論 非酒精性脂肪性肝病是影響急性胰腺炎嚴(yán)重程度的獨(dú)立危險(xiǎn)因素,且非酒精性脂肪性肝病的嚴(yán)重程度與急性胰腺炎的病情嚴(yán)重程度呈正相關(guān)。
Abstract:
Objective To explore the correlation between nonalcoholic fatty liver disease(NAFLD) and the severity of acute pancreatitis(AP). Methods The clinical datas of 331 AP inpatients in our hospital were collected and divided into mild acute pancreatitis(MAP), moderate severe acute pancreatitis(MSAP) and severe acute pancreatitis(SAP) according to the severity. Multiple logistic regression analysis was performed on the influencing factors of AP severity. Then the patients were divided into non-NAFLD group and NAFLD group to compare the relationship between NAFLD and AP severity. Finally, the non-NAFLD group was excluded, and the NAFLD group was divided into mild NAFLD, moderate NAFLD and severe NAFLD according to the severity. The Chi-square linear trend test was conducted for the severity of NAFLD and AP.Results NAFLD was an independent risk factor affecting the severity of AP(r=1.177,P<0.05). AP condition aggravated with the severity of NAFLD(χ2=8.605,P<0.05). Conclusion Nonalcoholic fatty liver disease is an independent risk factor affecting the severity of acute pancreatitis, and the severity of acute pancreatitis is strongly associated with the severity of nonalcoholic fatty liver disease.

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備注/Memo

備注/Memo:
1 福建省立金山醫(yī)院內(nèi)科; 2 福建省立醫(yī)院消化內(nèi)科; 3 通信作者
更新日期/Last Update: 2023-02-15