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[1]黃建明,魏恩煥,李增.經(jīng)鼻雙相正壓通氣治療早產(chǎn)兒呼吸暫停臨床觀察[J].福建醫(yī)藥雜志,2021,43(01):22-25.
　HUANG Jianming,WEI Enhuan,LI Zeng..Clinical observation on the treatment of premature infants with apnea by nasal biphasic positive pressure ventilation[J].FUJIAN MEDICAL JOURNAL,2021,43(01):22-25.
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經(jīng)鼻雙相正壓通氣治療早產(chǎn)兒呼吸暫停臨床觀察()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期數(shù):
2021年01期
頁碼:
22-25
欄目:
臨床研究
出版日期:
2021-02-10

文章信息/Info

Title:
Clinical observation on the treatment of premature infants with apnea by nasal biphasic positive pressure ventilation
文章編號:
1002-2600(2021)01-0022-04
作者:
黃建明; 魏恩煥; 李增
福建醫(yī)科大學(xué)附屬三明第一醫(yī)院兒科(三明 365000)
Author(s):
HUANG Jianming; WEI Enhuan; LI Zeng.
Department of Pediatrics,Sanming First Hospital affiliated to Fujian Medical University,Sanming,Fujian 365000,China
關(guān)鍵詞:
雙相正壓通氣;  持續(xù)氣道正壓通氣;  早產(chǎn)兒;  呼吸暫停
Keywords:
Biphasic positive pressure ventilation;  continuous positive airway pressure ventilation;  premature babies;  apnea
分類號:
R722.6
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 觀察使用經(jīng)鼻雙相正壓通氣對治療早產(chǎn)兒呼吸暫停的臨床效果。方法 選取2017年10月至2018年6月我院治療的86例原發(fā)性及繼發(fā)性呼吸暫停早產(chǎn)兒,隨機數(shù)字表法分為治療組及對照組,分別使用經(jīng)鼻雙相正壓通氣(biphasic)和經(jīng)鼻持續(xù)氣道正壓通氣(nasal continuous positive airway pressure,NCPAP)治療,兩組患兒性別、胎齡、出生體質(zhì)量、產(chǎn)前使用激素、分娩方式方面比較,差異無統(tǒng)計學(xué)意義(P>0.05),統(tǒng)計學(xué)分析兩組無創(chuàng)通氣時間、并發(fā)癥、改用有創(chuàng)機械通氣例數(shù)、吸氧時間、繼發(fā)感染和動脈導(dǎo)管未閉發(fā)生率。結(jié)果 經(jīng)鼻雙相正壓通氣治療組患兒與NCPAP對照組比較,其無創(chuàng)通氣時間、并發(fā)癥、改用有創(chuàng)機械通氣例數(shù)和吸氧時間明顯減少,兩組比較差異均有統(tǒng)計學(xué)意義(P<0.05); 而兩組繼發(fā)感染和動脈導(dǎo)管未閉發(fā)生率比較,差異無統(tǒng)計學(xué)意義(P>0.05)。結(jié)論 經(jīng)鼻雙相正壓通氣相比于NCPAP,具有一定優(yōu)勢,可替代NCPAP作為早產(chǎn)兒呼吸暫停的首選治療措施之一,及早使用可減少并發(fā)癥的發(fā)生,并可避免應(yīng)用有創(chuàng)機械通氣。
Abstract:
Objects To observe the clinical effect of transnasal biphasic positive pressure ventilation in the treatment of premature infants with apnea.Methods Selection in October 2017 to June 2018, the hospital treatment of 86 cases of primary and secondary apnea premature, which was divided into two groups by random number table respectively applied nasally dual phase positive pressure ventilation(Biphasic)and Nasal continuous positive airway pressure(NCPAP)treatment, two groups of children with gender, gestational age, birth weight, antenatal corticosteroids, childbirth way, there was no statistically significant difference(P>0.05).The non-invasive ventilation time, complications, cases of switching to invasive mechanical ventilation, oxygen inhalation time, secondary infection and incidence of patent ductus arteriosus were analyzed.Results Children treated with nasal biphasic positive pressure ventilation were compared with NCPAP control group,its non-invasive ventilation time, complications, cases of switching to invasive mechanical ventilation and oxygen absorption time were significantly reduced,the differences between the two groups were statistically significant(P<0.05); there was no statistically significant difference in the incidence of secondary infection and patent ductus arteriosus between the two groups(P>0.05).Conclusion Compared with NCPAP, transnasal biphasic positive pressure ventilation has obvious advantages, which can replace NCPAP as one of the first treatment measures for premature infants with apnea.Early use can reduce the occurrence of complications and avoid the use of invasive mechanical ventilation.

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更新日期/Last Update: 2021-02-10