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[1]王 薇 任 彥 付肖巖.內(nèi)鏡下金屬鈦夾聯(lián)合腎上腺素注射治療老年ANVUGIB的 臨床研究[J].福建醫(yī)藥雜志,2019,41(04):9-12.
　WANG Wei,REN Yan,FU Xiaoyan.Clinical study of combination therapy of epinephrine injection with endoscopic hemoclip in the treatment of the elderly patients with acute non-variceal upper gastrointestinal bleeding[J].FUJIAN MEDICAL JOURNAL,2019,41(04):9-12.
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內(nèi)鏡下金屬鈦夾聯(lián)合腎上腺素注射治療老年ANVUGIB的 臨床研究()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期數(shù):
2019年04期
頁碼:
9-12
欄目:
臨床研究
出版日期:
2019-08-15

文章信息/Info

Title:
Clinical study of combination therapy of epinephrine injection with endoscopic hemoclip in the treatment of the elderly patients with acute non-variceal upper gastrointestinal bleeding
文章編號(hào):
1002-2600(2019)04-0009-04
作者:
王 薇 任 彥 付肖巖
福建中醫(yī)藥大學(xué)附屬第二人民醫(yī)院消化內(nèi)科(福州 350003)
Author(s):
WANG Wei;  REN Yan;  FU Xiaoyan
Department of Gastroenterology, the Second Affiliated Peoples Hospital,Fujian University of Traditional Chinese Medicine,Fuzhou, Fujian 350003,China
關(guān)鍵詞:
上消化道出血;  金屬鈦夾;  腎上腺素;  止血;  老年患者
Keywords:
acute upper gastrointestinal bleeding;  hemoclip;  epinephrine;  hemostasis;  elderly patients
分類號(hào):
R573.2
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 觀察內(nèi)鏡下金屬鈦夾聯(lián)合腎上腺素注射治療老年急性非靜脈曲張性上消化 道出血(ANVUGIB)的臨床效果。方法 收集2013年1月至2017年12月293例ANVUGIB患者臨床資 料,其中,202例接受內(nèi)鏡下腎上腺素注射治療(腎上腺素注射組),91例接受內(nèi)鏡下金屬鈦夾聯(lián) 合腎上腺素注射治療(聯(lián)合治療組)。評(píng)估兩組初次止血率、再出血率、外科手術(shù)率、30天死 亡率和住院時(shí)間長短。結(jié)果 腎上腺素注射組和聯(lián)合治療組:初次止血率分別達(dá)到83.17%和 95.6%(P<0.05); 再出血率(14.85% vs 4.39%)和住院時(shí)間也有顯著改變 (P<0.05); 外科手術(shù)率無顯著改變,分別為5.45% vs 1.09%; 30天死亡率 相當(dāng)(1.98% vs 1.09%); 均未發(fā)現(xiàn)明顯的內(nèi)鏡治療并發(fā)癥。 結(jié)論 內(nèi)鏡下金屬鈦夾 聯(lián)合腎上腺素注射治療是一種止血效果顯著且安全的方法。
Abstract:
Objective To validate the efficacy of endoscopic hemoclips in combination with epinephrine injection in the treatment of the elderly patients with Acute Non-variceal Upper Gastrointestinal Bleeding(ANVUGIB), and to compare the clinical outcomes between patients treated with such a combination therapy and those treated with epinephrine injection alone.Methods Between February 1st 2013 and December 31st 2017, a total of 293 elderly patients with ANVUGIB were enderwent endoscopic therapy.Among these, 202 patients received epinephrine injection therapy(epinephrine injection group)while 91 patients received combination therapy of epinephrine injection with endoscopic hemoclip(combined treatment group).Primary hemostasis rates, re-bleeding rates, surgical rate, 30 -day mortality and hospitalization time were evaluated in both groups.Results The initial hemostasis of patients in epinephrine and endoscopic hemoclip plus epinephrine achieved 83.17% and 95.6% respectively(P<0.05).We detected significant difference in rate of re-bleeding(14.85% vs 4.39%)and the hospitalization time also changed significantly(P<0.05).However,there was no significant difference in the proportions of patients who required surgery, 5.45% vs 1.09%, respectively.And mortality in 30d was equal (1.98% vs 1.09%)in the two groups.No obvious complications from endoscopic treatment were observed in either group.Conclusion Combination therapy of epinephrine injection with endoscopic hemoclip application is an effective and safe method.

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更新日期/Last Update: 2019-08-15