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[1]陳意玲,黃美虹,黃珊珊,等.單點(diǎn)脈搏波傳導(dǎo)速度在晚發(fā)型子癇前期孕婦頸動(dòng)脈功能評(píng)估中的應(yīng)用[J].福建醫(yī)藥雜志,2025,47(04):11-14.[doi:10.20148/j.fmj.2025.04.003]
　CHEN Yiling,HUANG Meihong,HUANG Shanshan,et al.Application of singlepulse wave velocity in carotid artery function assessment of pregnant women with late-onset preeclampsia[J].FUJIAN MEDICAL JOURNAL,2025,47(04):11-14.[doi:10.20148/j.fmj.2025.04.003]
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單點(diǎn)脈搏波傳導(dǎo)速度在晚發(fā)型子癇前期孕婦頸動(dòng)脈功能評(píng)估中的應(yīng)用()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
47
期數(shù):
2025年04期
頁(yè)碼:
11-14
欄目:
臨床研究
出版日期:
2025-04-20

文章信息/Info

Title:
Application of singlepulse wave velocity in carotid artery function assessment of pregnant women with late-onset preeclampsia
文章編號(hào):
1002-2600(2025)04-0011-04
作者:
陳意玲1; 黃美虹1; 黃珊珊1; 林金淼1; 蔡名利1; 李拾林2; 呂國(guó)榮2
1 福建省晉江市醫(yī)院(上海市第六人民醫(yī)院福建醫(yī)院),泉州 362200; 2 福建醫(yī)科大學(xué)附屬第二醫(yī)院,泉州 362000
Author(s):
CHEN Yiling1;  HUANG Meihong1;  HUANG Shanshan1;  LIN Jinmiao1;  CAI Mingli1;  LI Shilin2;  LYU Guorong2
1Jinjiang Municipal Hospital, Fujian Province(Shanghai Sixth People's Hospital Fujian Hospital), Quanzhou, Fujian 362200, China; 2Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China
關(guān)鍵詞:
單點(diǎn)脈搏波傳導(dǎo)速度;  頸動(dòng)脈彈性;  晚發(fā)型子癇前期
Keywords:
single pulse wave velocity;  carotid artery elasticity;  late-onset preeclampsia
分類號(hào):
R445.1
DOI:
10.20148/j.fmj.2025.04.003
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 探討單點(diǎn)脈搏波傳導(dǎo)速度β(PWVβ)對(duì)晚發(fā)型子癇前期(PE)患者頸動(dòng)脈血管彈性功能的評(píng)價(jià)作用。方法 選取晉江市醫(yī)院2023年1月至2024年6月孕35～40+6周的孕婦作為研究對(duì)象,最終納入86例正常妊娠孕婦和58例晚發(fā)型PE患者。對(duì)所有受試者均在產(chǎn)前記錄基礎(chǔ)臨床數(shù)據(jù),并進(jìn)行了雙側(cè)頸總動(dòng)脈的超聲檢查評(píng)估。利用M型超聲技術(shù),精確測(cè)量左側(cè)頸總動(dòng)脈中段的收縮末期內(nèi)徑(Ds)與舒張末期內(nèi)徑(Dd)。同時(shí),運(yùn)用血管內(nèi)中膜定量分析(QIMT)技術(shù)測(cè)量左側(cè)頸總動(dòng)脈中段的平均內(nèi)中膜厚度(IMT),并計(jì)算PWVβ。對(duì)PWVβ與各測(cè)量指標(biāo)的相關(guān)性進(jìn)行分析,比較正常妊娠與PE兩組之間的差異,同時(shí)進(jìn)行多因素logistic回歸分析。結(jié)果 所有受試者PWVβ與體重、身體質(zhì)量指數(shù)(BMI)、收縮壓、舒張壓、IMT、Dd及 Ds均呈正相關(guān)(r=0.324、0.413、0.582、0.431、0.297、0.335、0.550)。晚發(fā)型PE組體重、BMI、Ds、Dd、IMT及PWVβ均較對(duì)照組增加(均P<0.05),其中BMI、PWVβ及IMT均為PE發(fā)生的獨(dú)立危險(xiǎn)因素[(OR=3.752,95%CI(1.776,7.924),P<0.05; OR=5.882,95%CI(2.141,16.157),P<0.05; OR=6.285,95%CI(2.269,17.409),P<0.05)]。結(jié)論 應(yīng)用PWVβ可以定量評(píng)估晚發(fā)型PE患者的頸動(dòng)脈彈性。晚發(fā)型PE患者孕期頸動(dòng)脈PWVβ增加,頸動(dòng)脈硬度增加,彈性功能已經(jīng)受損。
Abstract:
Objective To investigate the effect of single pulse wave velocity β(PWVβ)on carotid artery elasticity function in patients with late-onset preeclampsia(PE).Methods Pregnant women from 35 weeks to 40+6 weeks of gestation in Jinjiang Municipal Hospital from January 2023 to June 2024 were selected as the research objects.This study included 86 normal pregnant women and 58 participants with late-onset preeclampsia(PE).The basic clinical data before delivery were recorded for all the subjects and the bilateral common carotid arteries were evaluated by ultrasound.The end-systolic diameter(Ds)and end-diastolic diameter(Dd)of the middle segment of the left common carotid artery were accurately measured by M-mode ultrasound.At the same time, the mean intima-media thickness(IMT)of the middle segment of the left common carotid artery was measured by using the quantitative analysis of intima-media(QIMT)technique, and PWVβ was calculated.The correlation between PWVβ and each measurement index was analyzed, and the difference between normal pregnancy and PE was compared.At the same time, multivariate logistic regression analysis was performed.Results PWVβ was positively correlated with body weight, body mass index(BMI), systolic blood pressure, diastolic blood pressure, IMT, Dd and Ds in all subjects(r=0.324, 0.413, 0.582, 0.431, 0.297, 0.335, 0.550).The body weight, BMI, Ds, Dd, IMT and PWVβ in the late-onset PE group were higher than those in the control group(all P<0.05).BMI, PWVβ and IMT were independent risk factors for PE [OR=3.752,95%CI(1.776,7.924), P<0.05; OR=5.882,95%CI(2.141,16.157), P<0.05; OR=6.285,95%CI(2.269,17.409), P<0.05)].Conclusion PWVβ can be used to quantitatively evaluate the carotid artery elasticity in patients with late-onset PE.The PWVβ of carotid artery in patients with late-onset PE increased during pregnancy, the hardness of carotid artery increased, and the elastic function was impaired.

參考文獻(xiàn)/References:

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備注/Memo

備注/Memo:
基金項(xiàng)目:泉州科技局計(jì)劃項(xiàng)目(2023N021S); 晉江市醫(yī)院(上海市第六人民醫(yī)院福建醫(yī)院)計(jì)劃項(xiàng)目(2022LC01)
通信作者:呂國(guó)榮,Email: [email protected]
更新日期/Last Update: 2025-04-20