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[1]查小云,魏長順,吳金枝,等.新診斷2型糖尿病患者血C肽水平與10年內(nèi)動脈粥樣硬化性心血管疾病發(fā)生風(fēng)險的相關(guān)性分析[J].福建醫(yī)藥雜志,2024,46(08):17-21.[doi:10.20148/j.fmj.2024.08.005]
 ZHA Xiaoyun,WEI Changshun,WU Jinzhi,et al.Association between C-peptide level and 10-year risk of ASCVD in patients with newly diagnosed type 2 diabetes mellitus[J].FUJIAN MEDICAL JOURNAL,2024,46(08):17-21.[doi:10.20148/j.fmj.2024.08.005]
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新診斷2型糖尿病患者血C肽水平與10年內(nèi)動脈粥樣硬化性心血管疾病發(fā)生風(fēng)險的相關(guān)性分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
46
期數(shù):
2024年08期
頁碼:
17-21
欄目:
臨床研究
出版日期:
2024-12-20

文章信息/Info

Title:
Association between C-peptide level and 10-year risk of ASCVD in patients with newly diagnosed type 2 diabetes mellitus
文章編號:
1002-2600(2024)08-0017-05
作者:
查小云魏長順吳金枝謝良孝賴鵬斌
福建醫(yī)科大學(xué)附屬漳州市醫(yī)院內(nèi)分泌代謝一科,漳州 363000
Author(s):
ZHA XiaoyunWEI ChangshunWU JinzhiXIE LiangxiaoLAI Pengbin
The First Department of Endocrinology and Metabolism, Zhangzhou Hospital Affiliated to Fujian Medical University, Zhangzhou, Fujian 363000, China
關(guān)鍵詞:
2型糖尿病 空腹C肽 ASCVD風(fēng)險
Keywords:
type 2 diabetes fasting C-peptide risk of ASCVD
分類號:
R589.1
DOI:
10.20148/j.fmj.2024.08.005
文獻標志碼:
B
摘要:
目的 分析新診斷2型糖尿病(T2DM)患者血清C肽水平對10年內(nèi)發(fā)生動脈粥樣硬化性心血管疾病(ASCVD)的風(fēng)險的影響。方法 選取新診斷T2DM患者345例,根據(jù)空腹C肽(FCP)水平四分位數(shù)將患者分為4組,應(yīng)用China-PAR模型評估10年內(nèi)發(fā)生ASCVD的風(fēng)險。結(jié)果 高FCP水平(>0.980 ng/mL)與較高的10年ASCVD風(fēng)險相關(guān),且這種關(guān)系受性別和體重影響。多元線性回歸分析顯示,校正性別、年齡、BMI、糖化血紅蛋白等混雜因素后,FCP仍然能正向預(yù)測10年ASCVD風(fēng)險。結(jié)論 高FCP水平是新診斷T2DM患者未來ASCVD風(fēng)險的一個危險因素。
Abstract:
Objective To analyze the impact of serum C-peptide levels in patients with newly diagnosed type 2 diabetes(T2DM)on the 10-year risk of atherosclerotic cardiovascular disease(ASCVD).Methods A total of 345 patients with newly diagnosed T2DM were selected and categorized into four groups based on fasting C-peptide(FCP)level quartiles.The China-PAR model was employed to evaluate the 10-year ASCVD risk.Results Elevated FCP levels(greater than 0.980 ng/ml)were found to be associated with an increased 10-year ASCVD risk with this relationship being moderated by gender and weight.Multiple linear regression analysis indicated that, after adjusting confounding factors such as gender, age, BMI, and glycosylated hemoglobin, FCP levels remained a positive predictor of 10-year ASCVD risk.Conclusion High FCP levels constitute a significant risk factor for future ASCVD in patients with newly diagnosed T2DM.

參考文獻/References:

[1] JIA W, WENG J, ZHU D, et al.Standards of medical care for type 2 diabetes in China 2019[J].Diabetes Metab Res Rev, 2019, 35(6): e3158.
[2] VIIGIMAA M, SACHINIDIS A, TOUMPOURLEKA M, et al.Macrovascular complications of type 2 diabetes mellitus[J].Curr Vasc Pharmacol, 2020, 18(2): 110-116.
[3] ARNETT D K, BLUMENTHAL R S, ALBERT M A, et al.2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: Executive summary: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines[J].Circulation, 2019, 140(11): e563-e595.
[4] STANDL E, JANKA H U.High serum insulin concentrations in relation to other cardiovascular risk factors in macrovascular disease of type 2 diabetes[J].Horm Metab Res Suppl, 1985, 15: 46-51.
[5] GEDEBJERG A, BJERRE M, KJAERGAARD A D, et al.CRP, C-Peptide, and risk of first-time cardiovascular events and mortality in early type 2 diabetes: A Danish cohort study[J].Diabetes Care, 2023, 46(5): 1037-1045.
[6] JAHROMI M K, AHMADIRAD H, JAMSHIDI S, et al.The association of serum C-peptide with the risk of cardiovascular events: a meta-analysis and systematic review[J].Diabetol Metab Syndr, 2023, 15(1): 168.
[7] WAHAB M A, ALHABIBI A M, SAKR A K, et al.The correlation Between C-peptide and severity of peripheral atherosclerosis in type 2 diabetes mellitus[J].Diabetes Metab Syndr Obes, 2023, 16: 2617-2625.
[8] WANG Y, WAN H, CHEN Y, et al.Association of C-peptide with diabetic vascular complications in type 2 diabetes[J].Diabetes Metab, 2020, 46(1): 33-40.
[9] TOFFOLO G, DE GRANDI F, COBELLI C.Estimation of beta-cell sensitivity from intravenous glucose tolerance test C-peptide data.Knowledge of the kinetics avoids errors in modeling the secretion[J].Diabetes, 1995, 44(7): 845-854.
[10] TOPRAK K, KAPLANGORAY M, PALICE A.The impact of C-peptide and diabetes mellitus on coronary ectasia and effect of coronary ectasia and C-peptide on long-term outcomes: A retrospective cohort study[J].Int J Clin Pract, 2022, 2022: 7910566.
[11] QIN J, SUN R, DING D.Effects of serum C-peptide level on blood lipid and cardiovascular and cerebrovascular injury in patients with type 2 diabetes mellitus: A Meta-analysis[J].Contrast Media Mol Imaging, 2022, 2022: 6314435.
[12] YAN S T, SUN J, GU Z Y, et al.The bidirectional association of C-peptide with cardiovascular risk in nondiabetic adults and patients with newly diagnosed type 2 diabetes mellitus: a retrospective cohort study[J].Cardiovasc Diabetol, 2022, 21(1): 201.
[13] KAUTZKY-WILLER A, LEUTNER M, HARREITER J.Sex differences in type 2 diabetes[J].Diabetologia, 2023, 66(6): 986-1002.
[14] LIU J, JIN X, LIU W, et al.The risk of long-term cardiometabolic disease in women with premature or early menopause: A systematic review and meta-analysis[J].Front Cardiovasc Med, 2023, 10: 1131251.
[15] SHI S, NI L, TIAN Y, et al.Association of obesity indices with diabetic kidney disease and diabetic retinopathy in type 2 diabetes: A real-world study[J].J Diabetes Res, 2023, 2023: 3819830.
[16] AUSK K J, BOYKO E J, IOANNOU G N.Insulin resistance predicts mortality in nondiabetic individuals in the U.S[J].Diabetes Care, 2010, 33(6): 1179-1185.
[17] PATEL N, TAVEIRA T H, CHOUDHARY G, et al.Fasting serum C-peptide levels predict cardiovascular and overall death in nondiabetic adults[J].J Am Heart Assoc, 2012, 1(6): e3152.
[18] CHEN J, HUANG Y, LIU C, et al.The role of C-peptide in diabetes and its complications: an updated review[J].Front Endocrinol(Lausanne), 2023, 14: 1256093.
[19] LEE S K, LEE J O, KIM J H, et al.C-peptide stimulates nitrites generation via the calcium-JAK2/STAT1 pathway in murine macrophage Raw264.7 cells[J].Life Sci, 2010, 86(23-24): 863-868.
[20] MARX N, WALCHER D, RAICHLE C, et al.C-peptide colocalizes with macrophages in early arteriosclerotic lesions of diabetic subjects and induces monocyte chemotaxis in vitro[J].Arterioscler Thromb Vasc Biol, 2004, 24(3): 540-545.

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備注/Memo

備注/Memo:
通信作者:賴鵬斌,Email:[email protected]
更新日期/Last Update: 2024-12-20