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[1]林康昵.腫瘤重癥監(jiān)護(hù)室膿毒癥患者預(yù)后影響因素分析[J].福建醫(yī)藥雜志,2024,46(05):14-17.[doi:10.20148/j.fmj.2024.05.004]
　LIN Kangni.Risk factors for sepsis patients with malignant tumor in intensive care unit[J].FUJIAN MEDICAL JOURNAL,2024,46(05):14-17.[doi:10.20148/j.fmj.2024.05.004]
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腫瘤重癥監(jiān)護(hù)室膿毒癥患者預(yù)后影響因素分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
46
期數(shù):
2024年05期
頁(yè)碼:
14-17
欄目:
臨床研究
出版日期:
2024-10-15

文章信息/Info

Title:
Risk factors for sepsis patients with malignant tumor in intensive care unit
文章編號(hào):
1002-2600(2024)05-0014-04
作者:
林康昵
福建醫(yī)科大學(xué)腫瘤臨床醫(yī)學(xué)院 福建省腫瘤醫(yī)院重癥醫(yī)學(xué)科,福州 350014
Author(s):
LIN Kangni
Department of Critical Care Medicine, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian 350014, China
關(guān)鍵詞:
膿毒癥;  惡性腫瘤;  重癥醫(yī)學(xué);  橫斷面研究
Keywords:
sepsis;  malignant tumor;  critical care medicine;  cross-sectional survey
分類號(hào):
R73
DOI:
10.20148/j.fmj.2024.05.004
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 分析腫瘤膿毒癥患者的預(yù)后影響因素。方法 收集2021年1-6月在福建省腫瘤醫(yī)院重癥監(jiān)護(hù)室(ICU)進(jìn)行治療的膿毒癥患者的臨床數(shù)據(jù),對(duì)出現(xiàn)膿毒癥的腫瘤患者的人口學(xué)資料、感染情況、ICU相關(guān)評(píng)分等進(jìn)行分析,并通過Cox比例風(fēng)險(xiǎn)回歸對(duì)90 d死亡率進(jìn)行危險(xiǎn)因素分析。結(jié)果 腫瘤膿毒癥患者最常見的原發(fā)腫瘤為食管癌(19%),最常見的感染部位為肺部感染(69%),平均急性生理學(xué)和慢性健康評(píng)估(APACHE-Ⅱ)評(píng)分為13.0±3.9,中位序貫器官衰竭(SOFA)評(píng)分為5。共19名患者于入住ICU后90 d內(nèi)死亡,90 d死亡率為32.8%。多因素分析結(jié)果提示,SOFA評(píng)分>8分為90 d死亡的危險(xiǎn)因素[HR=10.504,95%CI:(2.383,46.298),P=0.002]。結(jié)論 SOFA評(píng)分>8分為腫瘤膿毒癥患者預(yù)后的危險(xiǎn)因素。
Abstract:
Objective To analyze the prognostic risk factors for sepsis in tumor patients.Methods Clinical data of sepsis patients with cancer who underwent treatment in our department from January 2021 to June 2021 were collected. Demographic data, infection status, ICU related scores, and other information were analyzed. Cox proportional hazards regression was used to analyze risk factors for 90-day mortality.Results A total of 58 patients were included in this study. The most common primary tumor was esophageal cancer(19%), and the most common site of infection was lung infection(69%). The average acute physiology and chronic health assessment(APACHE-II)score was 13.0±3.9, and the median sequential organ failure assessment(SOFA)score was 5. A total of 19 patients died within 90 days of admission to the ICU, with a 90-day mortality rate of 32.8%. The multivariate analysis indicate that a SOFA score greater than eight was an independent risk factor for 90-day mortality [HR=10.504, 95%CI:(2.383, 46.298), P=0.002].Conclusion SOFA score>8 is an independent prognostic risk factor.

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更新日期/Last Update: 2024-10-15