參考文獻(xiàn)/References:
[1] Siegel R,Ward E,Brawley O,et al.Cancer statistics, 2011:the impact of eliminating socioeconomic and racial disparities on premature cancer deaths[J]. CA Cancer J Clin，2011,61(4):212-236.
[2] Leemans C R,Snijders P J F,Brakenhoff R H.Publisher correction: the molecular landscape of head and neck cancer[J]. Nat Rev Cancer，2018,18(10):662.
[3] Chaturvedi A K.Epidemiology and clinical aspects of HPV in head and neck cancers[J]. Head Neck Pathol，2012,6 (1):S16-24.
[4] Adel K, EI-Naggar,Chan J K,et al. WHO classification of head and neck tumor(4th)[M]. Lyon：IARC press, 2017, 136-138.
[5] Dyne E A V,Henley S J,Saraiya M,et al.Trends in human papillomavirus-associated cancers united states, 1999-2015[J]. MMWR Morb Mortal Wkly Rep，2018,67(33):918-924.
[6] Tong F,Geng J,Yan B,et al.Prevalence and prognostic significance of HPV in laryngeal squamous cell carcinoma in northeast China[J]. Cell Physiol Biochem，2018,49(1):206-216.
[7] Montalto F I, Amicis F D.Cyclin D1 in cancer: a molecular connection for cell cycle control, adhesion and invasion in tumor and stroma[J]. Cells，2020,9(12):2648.
[8] Tchakarska G,Sola B.The double dealing of cyclin D1[J]. Cell Cycle，2020,19(2):163-178.
[9] Xie B,Wang S,Jiang N,et al.Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance[J]. Cancer Lett，2019(443):56-66.
[10] Hermosilla V E,Salgado G,Riffo E,et al.SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes[J]. Mol Oncol，2018,12(7): 1026-1046.
[11] Ito T,Zimdahl B,Reya T.A SIRTing control over cancer stem cells[J]. Cancer Cell，2012,21(2):140-142.
[12] Tang T,Xiao Z,Shan G,et al.Descending-SHIP2-mediated radiosensitivity enhancement through PI3K/Akt signaling pathway in laryngeal squamous cell carcinoma[J]. Biomed Pharmacother，2019(118):109392.
[13] Gaykalova D A, Mambo E,Choudhary A,et al.Novel insight into mutational landscape of head and neck squamous cell carcinoma[J]. PLoS One，2014,9(3):93102.
[14] Xv C, Li X, Li T,et al.Effect of different PTEN status on PI3K/AKT pathway of endometrial cancer cell lines[J]. Journal of Sun Yat sen University (Medical Sciences)，2011,32(6):701-707.
[15] Zhang X, Wu J,Luo S,et al.FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms[J]. Oncotarget，2016,7(23): 34371-34383.