80年代土耳其译制电影,80年代外国电影|80年代外国电影有哪些_80年代外国经典电影在线播放地址是多少？

[1]陳曉菁,朱素芹,李榕珊,等.卵泡期長效長方案不同促性腺激素啟動(dòng)劑量助孕效果的比較[J].福建醫(yī)藥雜志,2022,44(03):16-19.
　CHEN Xiaojing,ZHU Suqin,LI Rongshan,et al.Comparison of assisted reproductive outcome of different gonadotropin initiation dose groups in follicular phase long-acting long protocol[J].FUJIAN MEDICAL JOURNAL,2022,44(03):16-19.
點(diǎn)擊復(fù)制

卵泡期長效長方案不同促性腺激素啟動(dòng)劑量助孕效果的比較()
分享到：

《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
44
期數(shù):
2022年03期
頁碼:
16-19
欄目:
臨床研究
出版日期:
2022-06-15

文章信息/Info

Title:
Comparison of assisted reproductive outcome of different gonadotropin initiation dose groups in follicular phase long-acting long protocol
文章編號:
1002-2600(2022)03-0016-04
作者:
陳曉菁; 朱素芹; 李榕珊; 姜雯雯1
福建省婦幼保健院 福建醫(yī)科大學(xué)婦兒臨床醫(yī)學(xué)院(福州 350001)
Author(s):
CHEN Xiaojing;  ZHU Suqin;  LI Rongshan;  JIANG Wenwen
College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian Maternity and Child Health Hospital, Fuzhou,Fujian 350001, China
關(guān)鍵詞:
卵泡期長效長方案;  低劑量促性腺激素;  臨床結(jié)局
Keywords:
follicular phase long-acting long protocol;  low dose gonadotropin;  clinical outcomes
分類號:
R711.6
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 探討接受輔助生殖技術(shù)中卵泡期長效長方案超促排卵治療的患者低劑量促性腺激素(gonadotropin,Gn)啟動(dòng)對助孕效果的影響。方法 收集于我中心接受助孕的1 289例患者臨床資料,按照Gn啟動(dòng)劑量分為低劑量Gn啟動(dòng)組894例,常規(guī)Gn啟動(dòng)組395例,將兩組患者的基本資料及臨床結(jié)局進(jìn)行統(tǒng)計(jì)分析。 結(jié)果 低劑量啟動(dòng)組的平均Gn起始劑量為(136.5±16.4)IU,常規(guī)劑量組為(207.0±27.1)IU,兩組間Gn起始劑量差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。低劑量組的Gn總量少于常規(guī)劑量組,兩者差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。 低劑量組的臨床妊娠率高于常規(guī)劑量組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05),而宮外孕率與早期流產(chǎn)率兩組差異無統(tǒng)計(jì)學(xué)意義(P均>0.05)。中度卵巢過度刺激綜合征(OHSS)發(fā)生率在低劑量組稍高于常規(guī)劑量組,而重度OHSS發(fā)生率在低劑量組稍低,但兩者間差異無統(tǒng)計(jì)學(xué)意義(P均>0.05)。 結(jié)論 卵泡期長效長方案中采用低劑量Gn啟動(dòng)超促排卵可以獲得更好的助孕效果,值得在臨床進(jìn)一步推廣應(yīng)用。
Abstract:
Objective To investigate the effect of low dose Gonadotropin(Gn)initiation on pregnancy outcome in patients undergoing ovarian hyperstimulation with follicular phase long-acting long protocol in assisted reproductive technology.Methods The clinical data of 1 289 patients who received assisted pregnancy in our center were collected and divided into low dose Gn initiation group(n=894)and conventional Gn initiation group(n=395)according to the dose of Gn initiation.The basic data and clinical outcomes of the two groups were statistically analyzed.Results The average Gn initial dose in the low-dose initiation group was(136.5±16.4)IU, and that in the conventional dose group was(207.0±27.1)IU.The difference in Gn initial dose between the two groups was statistically significant(P<0.05). The total amount of Gn in the low-dose group was lower than that in the conventional dose group, and the difference was statistically significant(P<0.05).The clinical pregnancy rate in the low dose group was higher than that in the conventional dose group, and the difference was statistically significant(P<0.05), while there was no significant difference in the ectopic pregnancy rate and early abortion rate between the two groups(P>0.05).The incidence of moderate ovarian hyperstimulation syndrome(OHSS)was slightly higher in the low-dose group than in the conventional dose group, while the incidence of severe OHSS was slightly lower in the low-dose group, but the difference was not statistically significant(P>0.05).Conclusion Low dose Gn in the follicular phase long-acting long protocol can achieve better clinical outcome and economic benefit, which is worth further promotion and exploration in clinical practice.

參考文獻(xiàn)/References:

[1] Van Rooij I A, Broekmans F J, Hunault C C, et al.Use of ovarian reserve tests for the prediction of ongoing pregnancy in couples with unexplained or mild male infertility[J].Reprod Biomed Online,2006,12(2): 182-190.
[2] Xi Q, Tao Y, Qiu M, et al.Comparison Between PPOS and GnRHa-Long Protocol in Clinical Outcome with the First IVF/ICSI Cycle: A Randomized Clinical Trial[J].Clin Epidemiol, 2020,12: 261-272.
[3] 陳彩虹, 郭藝紅.卵泡期長效長方案促排卵早期思考[J].生殖醫(yī)學(xué)雜志,2019,28(10): 1130-1132.
[4] 李文澍, 包洪初, 張偉, 等.卵泡期長效長方案改善子宮內(nèi)膜異位癥患者IVF/ICSI的臨床結(jié)局[J].中華生殖與避孕雜志,2021,41(6): 496-502.
[5] 柯張紅, 鄭備紅, 孫艷, 等.卵泡期長效長方案在高齡女性中的運(yùn)用分析[J].生殖醫(yī)學(xué)雜志,2021, 30(1): 19-24.
[6] 李娜, 師娟子.激動(dòng)劑長方案中卵巢過度刺激綜合征的預(yù)防[J].生殖醫(yī)學(xué)雜志,2015, 24(10): 783-789.
[7] Albuquerque L E, Saconato H, Maciel M C, et al.Depot versus daily administration of GnRH agonist protocols for pituitary desensitization in assisted reproduction cycles: a Cochrane Review[J].Hum Reprod,2003,18(10): 2008-2017.
[8] Christ J, Herndon C N, Yu B.Severe ovarian hyperstimulation syndrome associated with long-acting GnRH agonist in oncofertility patients[J]. Assist Reprod Genet,2021,38(3): 751-756.
[9] Brown J B.Pituitary control of ovarian function—concepts derived from gonadotrophin therapy[J].Aust N Z J Obstet Gynaecol,1978,18(1): 46-54.
[10] Fauser B C, Van Heusden A M.Manipulation of human ovarian function: physiological concepts and clinical consequences[J].Endocr Rev,1997,18(1): 71-106.
[11] 莫莉菁, 付偉平, 朱琴, 等.聯(lián)合指標(biāo)對多囊卵巢綜合征患者發(fā)生卵巢高反應(yīng)的預(yù)測價(jià)值[J].中國婦幼保健,2021,36(6): 1324-1328.
[12] Sarkar P, Ying L, Plosker S, et al.Duration of ovarian stimulation is predictive of in-vitro fertilization outcomes[J].Minerva Ginecol,2019,71(6): 419-426.
[13] Baker V L, Brown M B, Luke B, et al.Gonadotropin dose is negatively correlated with live birth rate: analysis of more than 650,000 assisted reproductive technology cycles[J].Fertil Steril,2015, 104(5): 1145-1152.

備注/Memo

備注/Memo:
1 通信作者,Email:[email protected]
更新日期/Last Update: 2022-06-15