80年代土耳其译制电影,80年代外国电影|80年代外国电影有哪些_80年代外国经典电影在线播放地址是多少？

[1]陳森華,章麗燕,羅銀珠,等.早產(chǎn)兒視網(wǎng)膜病變與血小板參數(shù)的相關(guān)性研究[J].福建醫(yī)藥雜志,2022,44(03):11-16.
　CHEN Senhua,ZHANG Liyan,LUO Yinzhu,et al.Study of platelet indices in preterm infants with retinopathy of prematurity[J].FUJIAN MEDICAL JOURNAL,2022,44(03):11-16.
點(diǎn)擊復(fù)制

早產(chǎn)兒視網(wǎng)膜病變與血小板參數(shù)的相關(guān)性研究()
分享到：

《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
44
期數(shù):
2022年03期
頁碼:
11-16
欄目:
臨床研究
出版日期:
2022-06-15

文章信息/Info

Title:
Study of platelet indices in preterm infants with retinopathy of prematurity
文章編號:
1002-2600(2022)03-0011-06
作者:
陳森華; 章麗燕; 羅銀珠; 劉惠敏; 陳玉華; 何濃濃; 馬笑影1
福建醫(yī)科大學(xué)附屬福州兒童醫(yī)院(福州 350005)
Author(s):
CHEN Senhua;  ZHANG Liyan;  LUO Yinzhu;  LIU Huimin;  CHEN Yuhua;  HE Nongnong;  MA Xiaoying
The Affiliated Fuzhou Children Hospital,Fujian Medical University,Fuzhou,Fujian 350005,China
關(guān)鍵詞:
早產(chǎn)兒;  早產(chǎn)兒視網(wǎng)膜病變;  血小板參數(shù);  危險因素
Keywords:
preterm infants;  retinopathy of prematurity;  platelet parameters;  risk factors
分類號:
R722.1
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 分析早產(chǎn)兒視網(wǎng)膜病變與血小板參數(shù)的相關(guān)性。方法 選擇我院新生兒重癥監(jiān)護(hù)病房收治的出生胎齡≤32 周的早產(chǎn)兒175例,依據(jù)眼底鏡篩查結(jié)果分為早產(chǎn)兒視網(wǎng)膜病變(ROP)組和無早產(chǎn)兒視網(wǎng)膜病變(非ROP)組,其中ROP組66例,胎齡28.5(27.43～29.75)周,出生體質(zhì)量1 100(917.5～1 362.5)g,輕度患兒34例,重度患兒32例; 非ROP組109例,胎齡30.71(29.14～31.43)周,出生體質(zhì)量1 480(1 195～1 700)g。回顧性分析兩組早產(chǎn)兒母親妊娠期情況、生后2個階段血小板參數(shù)、早產(chǎn)兒基本資料、并發(fā)癥及治療措施等指標(biāo)。結(jié)果 單因素回歸分析顯示出生胎齡、輔助生殖技術(shù)、新生兒窒息、出生體質(zhì)量、呼吸暫停、咖啡因、支氣管肺發(fā)育不良(BPD)、糖皮質(zhì)激素、敗血癥、2個階段血小板計數(shù)、血小板分布寬度和血小板質(zhì)量指數(shù)、總用氧時間、酸中毒、紅細(xì)胞和血小板輸注與ROP相關(guān)(P<0.05); 而母親年齡、不良孕產(chǎn)史、分娩方式、胎盤早剝/植入、胎膜早破、羊水、宮內(nèi)窘迫、妊娠糖尿病、妊娠期高血壓、子癇前期/子癇、使用激素促胎肺成熟、雙胎/多胎、兩個階段的血小板平均體積與ROP無明顯相關(guān)性(P>0.05)。多因素分析結(jié)果顯示酸中毒、出生胎齡、生后1周血小板分布寬度和生后1周血小板質(zhì)量指數(shù)與ROP相關(guān)(P<0.05)。結(jié)論 酸中毒、生后1周血小板分布寬度較大,生后1周血小板質(zhì)量指數(shù)較小,出生胎齡小是ROP發(fā)生的獨(dú)立危險因素。
Abstract:
Objective To determine the relationship between the retinopathy of prematurity(ROP)in preterm infants and platelet parameters. Methods A total of 175 preterm infants [gestational age(GA)≤32 weeks]in the neonatal intensive care unit of our hospital were included,they were divided into ROP group and non-ROP group, according to the results of ophthalmoscope screening, 66 preterm infants in the ROP group with the GA was [28.5(27.43-29.75)]weeks, the birth weight(BW)was 1 100(917.5-1 362.5)]g, among them 34 children with mild ROP, 32 children with severe ROP; 109 preterm infants in non-ROP group,the GA was [30.71(29.14-31.43)] weeks, the BW was[1 480(1 195-1 700)]g. The indexes about maternal pregnancy data, platelet parameters at two postnatal stages, basic informations of preterm infants,complications and therapeutic management were analyzed retrospectively.Results Univariate regression analysis showed that the GA, assisted reproductive technique, neonatal asphyxia, BW,apnea, caffeine use, bronchopulmonary dysplasia(BPD), glucocorticoid use, sepsis, platelet count(PLT)with platelet distribution width(PDW)and platelet mass index(PMI)at two stages, total oxygen time, acidosis, red blood cell transfusions and platelet transfusions were correlated with ROP(P<0.05).And there were no significant relationship with ROP in maternal age, adverse gestational history, delivery mode, placental abruption/implantation, premature rupture of membranes, cloudy amniotic fluid, intrauterine distress, gestational diabetes mellitus, hypertension during pregnancy, preeclampsia / eclampsia, use of glucocorticoid to promote fetal lung maturation, double / multiple births, mean platelet volume(MPV)at two stages(P>0.05). The results of multivariate regression analysis showed that acidosis, GA,PDW and PMI at one week after birth were correlative with ROP(P<0.05). Conclusion Acidosis, a largerer PDW at one week after birth and a smaller PMI at one week after birth, lower GA are independent risk factors for ROP.

參考文獻(xiàn)/References:

[1] Early Treatment For Retinopathy Of Prematurity Cooperative Group.Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial[J].Arch Ophthalmol,2003, 121(12):1684-1694.
[2] Blencowe H, Lawn J E, Vazquez T, et al.Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010[J].Pediatr Res, 2013, 74(Suppl 1):35-49.
[3] Roth A M.Retinal vascular development in premature infants[J].Am J Ophthalmol, 1977, 84(5):636-640.
[4] Eldweik L, Mantagos I S.Role of VEGF inhibition in the treatment of retinopathy of prematurity[J].Semin Ophthalmol,2016, 31(1/2):163-168.
[5] Italiano J E Jr, Richardson J L, Patel-Hett S, et al.Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet alpha granules and differentially released[J].Blood, 2008, 111(3):1227-1233.
[6] Jensen A K, Ying G S, Huang J, et al.Thrombocytopenia and retinopathy of prematurity[J].J AAPOS, 2011,15(1):3-4.
[7] Korkmaz L, Bastu(ˇoverg)O, Özdemir A, et al.Platelet mass index can be a reliable marker in predicting the prognosis of retinopathy of prematurity in very preterm infants[J].Pediatr Neonatol, 2018, 59(5):455-463.
[8] Del Rey Hurtado de Mendoza B, Esponera C B, Izquierdo Renau M, et al.Asymptomatic late thrombocytosis is a common finding in very preterm infants even in the absence of erythropoietin treatment[J].J Int Med Res, 2019, 47(4):1504-1511.
[9] 中國醫(yī)師協(xié)會新生兒科醫(yī)師分會.早產(chǎn)兒治療用氧和視網(wǎng)膜病變防治指南(修訂版)[J].發(fā)育醫(yī)學(xué)電子雜志,2016,4(4):196-198.
[10] Chen M L, Guo L, Smith L E, et al.High or low oxygen saturation and severe retinopathy of prematurity: a meta-analysis[J].Pediatrics, 2010, 125(6):1483-1492.
[11] Bashinsky A L.Retinopathy of Prematurity[J].N C Med J, 2017, 78(2):124-128.
[12] Chen Y, Leske D A, Zhang S, et al.Duration of acidosis and recovery determine preretinal neovascularization in the rat model of acidosis-induced retinopathy[J].Curr Eye Res,2002, 24(4):281-288.
[13] Hauspurg A K, Allred E N, Vanderveen D K, et al.Blood gases and retinopathy of prematurity: the ELGAN study[J].Neonatology, 2011, 99(2):104-111.
[14] 李月,代震宇,張德純.血小板分布寬度作為新型血小板活化特異性標(biāo)志物的評價[J].重慶醫(yī)科大學(xué)學(xué)報, 2011, 36(2):200-202.
[15] 李翠潔,葉天航,鄒毅,等.早產(chǎn)兒視網(wǎng)膜病變的發(fā)病機(jī)制研究進(jìn)展[J].湖北民族學(xué)院學(xué)報:醫(yī)學(xué)版, 2018, 35(1):63-66.
[16] Maione T E, Gray G S, Petro J, et al.Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides[J].Science, 1990, 247(4938):77-79.
[17] Iruela-Arispe M L, Bornstein P, Sage H.Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro[J].Proc Natl Acad Sci U S A, 1991, 88(11):5026-5030.
[18] Patzelt J, Langer H F.Platelets in angiogenesis[J].Curr Vasc Pharmacol,2012,10(5):570-577.
[19] Vinekar A, Hegde K, Gilbert C,et al.Do platelets have a role in the pathogenesis of aggressive posterior retinopathy of prematurity?[J].Retina, 2010, 30(4):20-23.
[20] Klement G L, Yip T T, Cassiola F, et al.Platelets actively sequester angiogenesis regulators[J].Blood, 2009, 113(12):2835-2842.
[21] Etulain J, Fondevila C, Negrotto S, et al.Platelet-mediated angiogenesis is independent of VEGF and fully inhibited by aspirin[J].Br J Pharmacol, 2013, 170(2):255-265.
[22] Etulain J, Negrotto S, Tribulatti M V, et al.Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors[J].PLoS One, 2014, 9(4):e96402.
[23] Cekmez F, Tanju I A, Canpolat F E, et al.Mean platelet volume in very preterm infants: a predictor of morbidities?[J].Eur Rev Med Pharmacol Sci, 2013, 17(1):134-137.
[24] Tao Y, Dong Y, Lu C W, et al.Relationship between mean platelet volume and retinopathy of prematurity[J].Graefes Arch Clin Exp Ophthalmol, 2015, 253(10):1791-1794.
[25] 孫慧清,李明超,余增淵,等.平均血小板體積與重度早產(chǎn)兒視網(wǎng)膜病的關(guān)系研究[J].中華新生兒科雜志, 2019, 34(1):29-33.
[26] 吳曉蓉,邵毅, 袁高樂,等.1型閾值前期和閾值期早產(chǎn)兒視網(wǎng)膜病變血小板參數(shù)分析[J].眼科新進(jìn)展, 2016, 36(2):129-132.
[27] 孫慧清,李明超, 余增淵,等.血小板減少對早產(chǎn)兒視網(wǎng)膜病變的影響[J].眼科新進(jìn)展, 2018, 38(8):779-782.
[28] Celik K, Ekinci D, Asena M, et al.Can Hematological Parameters be a Indicator Risk Factor in the Development of Retinopathy of Prematurity?[J].Klin Padiatr,2021, 233(5):216-220.

相似文獻(xiàn)/References:

[1]黃艷,葛品,周有峰.554例早產(chǎn)兒死亡原因分析[J].福建醫(yī)藥雜志,2021,43(01):90.

備注/Memo

備注/Memo:
基金項目:福州市2019年市級臨床重點(diǎn)專科建設(shè)項目(201912007)
1 通信作者
更新日期/Last Update: 2022-06-15