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[1]郭曉峰,朱鵬舉,王程毅,等.兒童重癥肺炎支原體肺炎185例影響因素分析[J].福建醫(yī)藥雜志,2021,43(06):1-5.
 GUO Xiaofeng,ZHU Pengju,WANG Chengyi,et al.Analysis of influencing factors of 185 children with severe mycoplasma pneumoniae pneumonia[J].FUJIAN MEDICAL JOURNAL,2021,43(06):1-5.
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兒童重癥肺炎支原體肺炎185例影響因素分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期數(shù):
2021年06期
頁碼:
1-5
欄目:
臨床研究
出版日期:
2021-12-15

文章信息/Info

Title:
Analysis of influencing factors of 185 children with severe mycoplasma pneumoniae pneumonia
文章編號(hào):
1002-2600(2021)06-0001-05
作者:
郭曉峰朱鵬舉1王程毅2趙涵3劉光華王世彪
上海交通大學(xué)醫(yī)學(xué)院附屬上海兒童醫(yī)學(xué)中心福建醫(yī)院 福建省婦幼保健院 福建醫(yī)科大學(xué)附屬醫(yī)院 福建省兒童醫(yī)院(福州 350011)
Author(s):
GUO Xiaofeng ZHU Pengju WANG Chengyi ZHAO Han LIU Guanghua WANG Shibiao
Department of Pediatrics, Fujian Children's Hospital,Fujian Maternity and Child Health Hospital,Affiliated Hospital of Fujian Medical University, Fujian Branch of Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine,Fuzhou,Fujian 350011, China
關(guān)鍵詞:
肺炎支原體重癥 三代死亡風(fēng)險(xiǎn)評(píng)分 兒童
Keywords:
mycoplasma pneumoniaseverity PRISM Ⅲ children
分類號(hào):
R563.1
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 探討重癥肺炎支原體肺炎(MPP)的影響因素。方法 回顧性分析我院2016年1月至2018年12月收治的185例重癥MPP患兒的臨床資料,并根據(jù)PRISM Ⅲ評(píng)分將患兒分為低危組(PRISM評(píng)分≤3分)91例、中危組(PRISM評(píng)分3~8分)71例和高危組(PRISM評(píng)分大于>8分)23例。結(jié)果 3組間臨床特征比較,2/3及更多的肺葉受累所占比例、2個(gè)或更多系統(tǒng)的肺外并發(fā)癥所占比例、氣管插管所占比例差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。3組間實(shí)驗(yàn)室檢查比較,血紅蛋白和前白蛋白(PA)水平降低,而紅細(xì)胞體積分布寬度(RDW)和D-二聚體(D-D)水平升高,差異均具有統(tǒng)計(jì)學(xué)意義(P<0.05)。在有序logistic回歸模型中,我們發(fā)現(xiàn)2個(gè)或更多系統(tǒng)肺外并發(fā)癥所占比例[OR=0.369,95%CI(0.161,0.848),P=0.019]、氣管插管所占比例[OR=0.451,95%CI(0.215,0.945),P=0.035]、RDW水平[OR=1.358,95%CI(1.154,1.598),P<0.001)]與PRISM Ⅲ評(píng)分呈正相關(guān),而PA水平[OR=0.883,95%CI(0.839,0.930),P<0.001]與PRISM Ⅲ評(píng)分呈負(fù)相關(guān)。結(jié)論 我們認(rèn)為2個(gè)或更多系統(tǒng)的肺外并發(fā)癥所占比例、氣管插管所占比例、RDW水平和PA水平是患兒重癥MPP的影響因素。
Abstract:
Objective This study is aimed to analyze influencing factors which could warn the progression of severe mycoplasma pneumoniae pneumonia(MPP).Methods We retrospectively reviewed the data of 185 children with severe MPP who were treated in our hospital between January 2016 and December 2018.We stratified the children according to PRISM Ⅲ scores, 91 cases were in the low group(≤3 scores), 71 cases were in the medium group(3-8 scores), and 23 cases were in the high group(>8 scores).Results There were statistical significances(P<0.05)in the proportions of those with 2/3 or more pulmonary lobes affected, extrapulmonary complications of two or more systems, and intubation among the three groups.Hemoglobin and pre-albumin levels decreased, while red blood cell volume distribution width(RDW)and D-dimer levels increased among the three groups, with statistical significance(P<0.05).In the ordered logistic regression model, there were positive correlations between extrapulmonary complications of two or more systems[OR=0.369,95%CI(0.161,0.848),P=0.019],intubation[OR=0.451,95%CI(0.215,0.945),P=0.035], RDW level[OR=1.358,95%CI(1.154,1.598),P<0.001)] and PRISM Ⅲ scores.In contrast, there was a negative correlation between pre-albumin level[OR=0.883,95%CI(0.839,0.930),P<0.001] and PRISM Ⅲ scores.Conclusion We consider extrapulmonary complications of two or more systems, intubation, RDW level, and pre-albumin level may be influencing factors of severe MPP.

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相似文獻(xiàn)/References:

[1]潘云虎,季志宇,劉國生,等.蘇黃止咳膠囊對減輕肺炎支原體肺部感染大鼠炎癥反應(yīng)的作用及機(jī)制探討[J].福建醫(yī)藥雜志,2021,43(01):124.

備注/Memo

備注/Memo:
1 福建省寧德市霞浦縣醫(yī)院兒科; 2 通信作者,Email:[email protected]; 3 福建醫(yī)科大學(xué)2018級(jí)學(xué)生
更新日期/Last Update: 2021-12-15