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[1]楊惠安,俞曉玲,官升燦,等.成人登革熱合并低鉀血癥的臨床特征及其影響因素分析[J].福建醫(yī)藥雜志,2021,43(03):10-14.
　YANG Huian,YU Xiaoling,GUAN Shengcan,et al.Analysis of clinical characteristics and influencing factors of hypokalemia in adult patients with dengue[J].FUJIAN MEDICAL JOURNAL,2021,43(03):10-14.
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成人登革熱合并低鉀血癥的臨床特征及其影響因素分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
43
期數(shù):
2021年03期
頁碼:
10-14
欄目:
臨床研究
出版日期:
2021-06-15

文章信息/Info

Title:
Analysis of clinical characteristics and influencing factors of hypokalemia in adult patients with dengue
文章編號:
1002-2600(2021)03-0010-05
作者:
楊惠安; 俞曉玲1; 官升燦; 葉寒輝2
福建醫(yī)科大學孟超肝膽醫(yī)院感染科(福州 350025)
Author(s):
YANG Huian;  YU Xiaoling;  GUAN Shengcan;  YE Hanhui
Department of Infectious Diseases,Mengchao Hepatobiliary Hospital of Fujian Medical University,Fuzhou,Fujian 350025,China
關(guān)鍵詞:
登革熱;  低鉀血癥;  危險因素
Keywords:
dengue;  hypokalemia;  risk factors
分類號:
R512.8 R373.3+3
文獻標志碼:
B
摘要:
目的 探討成人登革熱合并低鉀血癥的臨床特征,并分析其影響因素。方法 回顧性分析我院收治的363例成人登革熱的臨床資料,根據(jù)入院血鉀水平分為低鉀血癥組(<3.5 mmol/L)和正常血鉀組(3.5～5.3 mmol/L),采用單因素分析和多因素logistic回歸分析探討低鉀血癥發(fā)生的相關(guān)因素。結(jié)果 成人登革熱合并低鉀血組179例(49.31%),正常血鉀組184例(50.69%)。成人登革熱病例低鉀血癥組和正常血鉀組在乏力癥狀指標上差異有統(tǒng)計學意義(χ2=4.291,P=0.036),其余指標差異均無統(tǒng)計學意義(P>0.05)。經(jīng)單因素與多因素logistic回歸分析結(jié)果顯示,入院前病程≤3 d[OR=1.906,95%CI(1.247,2.914),P=0.003]、合并高血壓病[OR=2.166,95%CI(1.153,4.067),P=0.016]是成人登革熱患者低鉀血癥的危險因素。結(jié)論 成人登革熱患者低鉀血癥發(fā)生率高,尤其是疾病早期及合并高血壓患者,因此,在治療期間,應密切關(guān)注患者的血鉀情況并及時補鉀。
Abstract:
Objective To investigate the clinical characteristics and the influencing factors of hypokalemia in adult patients with dengue.Methods The clinical data of 363 patients with dengue in adults admitted to Mengchao Hepatobiliary Hospital of Fujian Medical University were retrospectively analyzed.The patients were divided into hypokalemia group(<3.5 mmol/L)and normal potassium group(≥3.5 mmol/L)based on the first serum potassium level.The influencing factors of hypokalemia were explored by univariate analysis and multivariate logistic regression analysis.Results Hypokalemia group accounted for 179 cases(49.31%),normal potassium group accounted for 184 cases(50.69%).There were statistically significant differences in fatigue symptoms between the hypokalemia group and the normal potassium group in adult patients with dengue(χ2=4.291,P=0.036),while there were no statistically significant differences in other indicators(P>0.05).The univariate and multivariate logistic regression analysis showed that the course of disease ≤3 days before admission[OR=1.906,95%CI(1.247,2.914),P=0.003] and basic disease hypertension [OR=2.166,95%CI(1.153,4.067),P=0.016] were the risk factors for hypokalemia among patients with dengue in adults.Conclusion The incidence of hypokalemia in adult patients with dengue is high,especially in the early stage of the disease and patients with hypertension.So during the treatment we should pay close attention to the serum potassium level of the patients and timely supplement potassium.

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備注/Memo

備注/Memo:
基金項目:福建省感染性疾病臨床重點專科建設項目; 福州市感染病醫(yī)學中心建設項目(2018080306)
1 藥學部; 2 通信作者,Email:[email protected]
更新日期/Last Update: 2021-06-15