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[1]陳彩鳳 鄭 焱 張丹群.C10orf99在扁平苔蘚中的表達(dá)和意義[J].福建醫(yī)藥雜志,2020,42(05):121-122.
 CHEN Caifeng,ZHENG Yan,ZHANG Danqun.Expression and significance of C10orf99 in skin lichen planus[J].FUJIAN MEDICAL JOURNAL,2020,42(05):121-122.
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C10orf99在扁平苔蘚中的表達(dá)和意義()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期數(shù):
2020年05期
頁碼:
121-122
欄目:
基礎(chǔ)研究
出版日期:
2020-10-20

文章信息/Info

Title:
Expression and significance of C10orf99 in skin lichen planus
文章編號:
1002-2600(2020)05-0121-03
作者:
陳彩鳳 鄭 焱1 張丹群2
福建醫(yī)科大學(xué)省立臨床醫(yī)學(xué)院 福建省立醫(yī)院皮膚科(福州 350001)
Author(s):
CHEN CaifengZHENG YanZHANG Danqun
Department of Dermatology, Fujian Provincial Hospital,Clinical Medical College of Fujian Medical University, Fuzhou,Fujian 350001, China
關(guān)鍵詞:
皮膚扁平苔蘚 C10orf99 免疫組化
Keywords:
lichen planus C10orf99 immunohistochemistry
分類號:
R758.65
文獻(xiàn)標(biāo)志碼:
A
摘要:
目的 檢測C10orf99在扁平苔蘚皮損中的表達(dá)情況,探討C10orf99在該病發(fā)病機(jī)制中的作用。方法 應(yīng)用免疫組化SP法檢測C10orf99在20例扁平苔蘚皮損組織和10例正常皮膚組織中的表達(dá)情況。結(jié)果 C10orf99在扁平苔蘚皮損中的表達(dá)水平明顯高于其在正常皮膚組織中的表達(dá)水平,差異有統(tǒng)計(jì)學(xué)意義(P<0.001)。結(jié)論 C10orf99在扁平苔蘚皮損中呈現(xiàn)高表達(dá),可能在扁平苔蘚的發(fā)生發(fā)展過程中起作用。
Abstract:
Objective To investigate the expression and significance of C10orf99 in lichen planus lesions.Methods Immunohistochemical method was carried out to detect the expression of C10orf99 in 20 patients with lichen planus and 10 specimens of normal skin.Results The expression of C10orf99 in the lesions of lichen planus was significantly higher than that in normal skin tissues, and the difference was statistically significant(P<0.001).Conclusion The expression of C10orf99 is increased in lichen planus and C10orf99 may play an important role in the occurrence and development of lichen planus.

參考文獻(xiàn)/References:

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備注/Memo

備注/Memo:
基金項(xiàng)目:國家自然科學(xué)基金青年科學(xué)基金項(xiàng)目(81903220) 1 西安交通大學(xué)第二附屬醫(yī)院皮膚科(西安 710049); 2 通信作者,Email: [email protected]
更新日期/Last Update: 2020-10-20