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[1]吳立忠 翁繩健 詹 洋 吳 星 鄭 萍 康榮彬 李煒明.強(qiáng)骨寶方對生物型全髖術(shù)后髖臼假體周圍骨密度的早期影響[J].福建醫(yī)藥雜志,2020,42(03):13-16.
　WU Lizhong,WENG Shengjian,ZHAN Yang,et al.Early effect of Qianggubao decoction on BMD around acetabular prosthsis after the cementless total hip arthroplasty[J].FUJIAN MEDICAL JOURNAL,2020,42(03):13-16.
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強(qiáng)骨寶方對生物型全髖術(shù)后髖臼假體周圍骨密度的早期影響()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期數(shù):
2020年03期
頁碼:
13-16
欄目:
臨床研究
出版日期:
2020-07-04

文章信息/Info

Title:
Early effect of Qianggubao decoction on BMD around acetabular prosthsis after the cementless total hip arthroplasty
文章編號:
1002-2600(2020)03-0013-04
作者:
吳立忠 翁繩健 詹 洋 吳 星 鄭 萍 康榮彬 李煒明1
廈門大學(xué)附屬福州第二醫(yī)院關(guān)節(jié)外科(福州 350007)
Author(s):
WU Lizhong; WENG Shengjian; ZHAN Yang; WU Xing; ZHENG Ping; KANG Rongbin; LI Weiming.
The Fuzhou Second Hospital Affiliated to Xiamen University,Fuzhou,Fujian 350007,China
關(guān)鍵詞:
強(qiáng)骨寶方;  骨密度;  全髖關(guān)節(jié)置換術(shù)
Keywords:
Qianggubao decoction;  bone mineral density;  total hip arthroplasty
分類號:
R681
文獻(xiàn)標(biāo)志碼:
A
摘要:
目的 探討強(qiáng)骨寶方對女性生物型全髖置換術(shù)后髖臼假體周圍骨密度的早期影響。方法 隨機(jī)將50例符合納入標(biāo)準(zhǔn)的全髖置換患者分為強(qiáng)骨寶方組和對照組,術(shù)后1周均開始口服鈣爾奇D 600 mg/d、羅蓋全0.25 μg /d,其中,強(qiáng)骨寶方組患者每日另加1劑強(qiáng)骨寶方顆粒劑沖服,對照組不使用其他抗骨質(zhì)疏松藥物,連續(xù)服用藥物3個(gè)月。兩組均于術(shù)后1周、術(shù)后3、6、12個(gè)月測定髖臼假體周圍分區(qū)骨密度,同時(shí)行髖關(guān)節(jié)功能評分。結(jié)果 47例患者獲得完整隨訪。術(shù)后兩組患者各分區(qū)骨密度均持續(xù)下降,Ⅲ區(qū)術(shù)后6個(gè)月及12個(gè)月強(qiáng)骨寶方組患者骨密度下降低于對照組,其差異有統(tǒng)計(jì)學(xué)意義(P<0.05),其余分區(qū)及時(shí)點(diǎn)骨密度比較的差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。兩組患者術(shù)后各時(shí)點(diǎn)髖關(guān)節(jié)功能評分比較的差異無統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論 中藥強(qiáng)骨寶方應(yīng)用于全髖關(guān)節(jié)置換術(shù)后可有效減少髖臼假體周圍骨密度的下降。
Abstract:
Objective To investigate the early effect of Qianggubao decoction on bone mineral density(BMD)around acetabular prosthesis after the female cementless total hip arthroplasty.Methods Fifty patients who met the inclusion criteria were divided into the Qianggubao group and the control group randomly.All patients took therapy of Caltrate D 600mg/d and Rocaltrol 0.25 μg /d one week after total hip arthroplasty(THA)and lasted for three months.At the same time Qianggubao group took Qianggubao granules one dose per day for three months.The control group didnt take other anti-osteoporosis drug.BMD around acetabular prosthesis was detected at the point of 1 week after THA, 3 months after THA, 6 months after THA and 12 months after THA. The hip function was assessed by Harris scoring system at the same time.Results A total of 47 patients finished the study.BMD of all zones declined continuously.The loss of BMD in Zone Ⅲ of the Qianggubao group was less than control group at time of 6 and 12 months after THA.The difference between the two groups was statistically significant(P<0.05).There was no significant difference in other zones and other point between the two groups(P> 0.05).There were no statistically significant differrences in Harris scores between the two groups at any point.Conclusion Qianggubao decoction can decrease the loss of BMD around acetabular prosthesis after the cementless THA.

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備注/Memo

備注/Memo:
基金項(xiàng)目:基金項(xiàng)目:福建省科技計(jì)劃引導(dǎo)性項(xiàng)目(2017D0001); 福州市科技計(jì)劃社會發(fā)展項(xiàng)目(2016-S-123-4)1 通信作者,Email:[email protected]
更新日期/Last Update: 2020-07-04