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[1]李 濱 歐陽秋芳 陳美華 王 永 郭進建.二維斑點追蹤技術(shù)評價健心顆粒對糖尿病心肌病患者左室功能的影響[J].福建醫(yī)藥雜志,2020,42(02):20-24.
　LI Bin,OUYANG Qiufang,CHEN Meihua,et al.Effect of jianxin granules on left ventricular function in patients with diabetic cardiomyopathy was evaluated by two-dimensional spot tracking technique[J].FUJIAN MEDICAL JOURNAL,2020,42(02):20-24.
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二維斑點追蹤技術(shù)評價健心顆粒對糖尿病心肌病患者左室功能的影響()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
42
期數(shù):
2020年02期
頁碼:
20-24
欄目:
臨床研究
出版日期:
2020-04-15

文章信息/Info

Title:
Effect of jianxin granules on left ventricular function in patients with diabetic cardiomyopathy was evaluated by two-dimensional spot tracking technique
文章編號:
1002-2600(2020)02-0020-05
作者:
李 濱 歐陽秋芳 陳美華 王 永 郭進建1
福建中醫(yī)藥大學附屬第二人民醫(yī)院心血管內(nèi)科(福州 350001)
Author(s):
LI Bin; OUYANG Qiufang; CHEN Meihua;  WANG Yong; GUO Jinjian.
Department of cardiology, the Second Peoples Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou,Fujian 350001, China
關(guān)鍵詞:
健心顆粒;  糖尿病心肌病;  斑點追蹤技術(shù);  心功能
Keywords:
jianxin granules;  diabetic cardiomyopathy;  spot tracking technology;  cardiac function
分類號:
R587.1; R540.4+5
文獻標志碼:
A
摘要:
目的 采用二維斑點追蹤技術(shù)評價健心顆粒對糖尿病心肌病(DCM)患者心室功能的影響。方法 選擇2017年1月至2019年12月于本院心血管內(nèi)科新確診的80名DCM患者為研究對象,分為觀察組和對照組,每組40例,兩組均給予常規(guī)西藥治療方案,觀察組在此基礎(chǔ)上給予健心顆粒,兩組療程為1個月。比較兩組患者在治療前后臨床癥狀、收縮壓、舒張壓、左室收縮期整體長軸峰值應(yīng)變、整體圓周峰值應(yīng)變、左室射血分數(shù)、NT-proBNP等指標變化情況。結(jié)果 觀察組臨床療效總有效率(85.0%)明顯高于對照組(60.0%)。治療后,兩組空腹血糖及NT-proBNP均顯著減低,但觀察組NT-proBNP、射血分數(shù)、左室收縮期整體長軸(圓周、徑向)峰值應(yīng)變改善情況明顯大于對照組。兩組間LA、LVDd、IVSd、LVPWd、E/A治療前后差異無統(tǒng)計學意義(P>0.05)。結(jié)論 健心顆粒在改善DCM左室結(jié)構(gòu)前,已明顯改善其心室功能; 二維斑點追蹤技術(shù)能夠早期準確地對治療效果進行評價,值得臨床推廣及應(yīng)用。
Abstract:
Objective The effect of jianxin granules on ventricular function in patients with diabetic cardiomyopathy(DCM)was evaluated by two-dimensional spot tracking technique.Methods A total of 80 newly diagnosed DCM patients from the department of cardiology, the Second Peoples Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January 2017 to December 2019 were selected as subjects.They were divided into the experimental group and the control group, with 40 participants in each group.Both groups were given the conventional western medicine treatment plan, and the experimental group was given jianxin granules on this basis.The treatment course of the two groups was 1 month.The changes of clinical symptoms, systolic blood pressure, diastolic blood pressure, left ventricular systolic overall long-axis peak strain, overall peripheral peak strain, left ventricular ejection fraction, nt-probnp and other indicators in the two groups before and after treatment were compared.Results The total effective rate(85.0%)of the experimental group was significantly higher than that of the control group(60.0%).After treatment, fasting glucose and nt-probnp were significantly reduced in both groups, but the experimental group nt-probnp, ejection fraction, left ventricular systolic overall long axis(circumference, radial)peak strain improvement was significantly greater than the control group.There were no significant differences in LA, LVDd, IVSd, LVPWd and E/A between the two groups before and after treatment.Conclusion Before improving the left ventricular structure of DCM, jianxin granules had significantly improved its ventricular function.The two-dimensional spot tracking technology can accurately evaluate the treatment effect in the early stage, which is worthy of clinical promotion and application.

參考文獻/References:

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備注/Memo

備注/Memo:
基金項目:第四批全國中醫(yī)優(yōu)秀人才項目(國中醫(yī)藥辦人教發(fā)[2017]24號); 國家自然科學基金(81973916); 福建省衛(wèi)生計生中青年骨干人才培養(yǎng)項目(2018-ZQN-71); 福建省自然科學基金(2019J01480)。第一作者:李濱,醫(yī)學碩士,中西醫(yī)結(jié)合醫(yī)師。1 通信作者:郭進建,醫(yī)學博士,主任醫(yī)師,Email:[email protected]
更新日期/Last Update: 2020-04-15