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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:

41

期數(shù):

2019年06期

頁碼:

19-135

欄目:

臨床研究

出版日期:

2019-12-25

文章信息/Info

Title:

Analysis of food intolerance-specific IgG antibodies in children before and after school age

文章編號:

1002-2600(2019)06-0019-04

作者:

張忠龍 吳汝香

福建省福州兒童醫(yī)院(福州 350005)

Author(s):

ZHANG Zhonglong; WU Ruxiang.

Fuzhou Children�搒 Hospital of Fujian Province, Fuzhou, Fujian 350005, China

關(guān)鍵詞:

學(xué)齡前后;  患兒;  食物不耐受;  IgG抗體

Keywords:

before and after school age;  children;  food intolerance;  IgG antibodies

分類號:

R593.1

文獻標(biāo)志碼:

B

摘要:

目的 探討學(xué)齡前后患兒食物不耐受表現(xiàn)形式及陽性率分布特征,為降低食物不耐受的發(fā)展提供科學(xué)喂養(yǎng)依據(jù)。方法 采用ELISA法對學(xué)齡前后1 626例消化道、皮膚疾病患兒進行常見的14種食物不耐受的特異性IgG抗體檢測,判斷級別,分析食物不耐受程度。結(jié)果 所有患兒IgG抗體陽性率為88.0%。兩種疾病患兒:不耐受陽性率相近(88.2%、86.9%); >3歲患兒以雞蛋檢出陽性率最高,分別為77.8%、69.9%,其次為牛奶,分別為61.9%、62.1%; ≤3歲患兒,以牛奶檢出陽性率最高,分別為77.6%、76.2%,其次為雞蛋,分別為56.5%、46.3%。多種食物不耐受陽性率從高到低依次為3種及以上、2種、1種。牛奶和雞蛋是引起中重度食物不耐受的主要食物,也是同一病種多種食物不耐受的主要食物。結(jié)論 消化道、皮膚兩種變應(yīng)性疾病患兒與食物不耐受關(guān)系密切,學(xué)齡前后食物不耐受表現(xiàn)形式不同,這為減少食物不耐受疾病發(fā)生,指導(dǎo)喂養(yǎng)提供了科學(xué)依據(jù)。

Abstract:

Objective To investigate the distribution patterns and positive rate distribution of food intolerance in children before and after school age, and to provide scientific feeding basis for reducing the development of food intolerance. Methods Enzyme-linked immunosorbent assay(ELISA)was used to detect 14 kinds of common food intolerance-specific IgG antibodies in children with digestive tract and skin diseases before and after school age.The grades were analyzed and the degree of food intolerance was analyzed. Results Among the 1 626 children, the positive rate of 14 kinds of food intolerance-specific IgG antibodies was 88.0%. The positive rate of intolerance was similar in children with two diseases(88.2%, 86.9%).For children >3 years old,the positive rate of egg detection was the highest in 77.8% and 69.9%,respectively. Followed by milk,which were 61.9% and 62.1%.For children ≤3 years old,the highest positive rate was detected in milk,which were 77.6% and 76.2%, followed by eggs, which were 56.5% and 46.3%,respectively. The positive rates of various food intolerances were three or more, two, and one from high to low. Milk and eggs were the main foods that cause moderate to severe food intolerance, and were the main foods that were intolerant to multiple foods of the same disease. Conclusion Children with digestive tract and skin allergic diseases are closely related to food intolerance.The pattern of food intolerance before and after school age is different, which provides a scientific basis for reducing the occurrence of food intolerance and guiding feeding.

備注/Memo

備注/Memo:

基金項目:福建省自然科學(xué)基金資助項目(2016J01436)1 通信作者

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更新日期/Last Update: 2019-12-25