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[1]陳瓊?cè)A 鄭敬陽(yáng) 張圳杰 林印濤 曾麗娥 林春燕 張 譚.嬰幼兒反復(fù)喘息136例病因分析[J].福建醫(yī)藥雜志,2019,41(06):12-15.
　CHEN Qionghua,ZHENG Jingyang,ZHANG Zhenjie,et al.Etiological analysis of recurrent wheezing in 136 infants[J].FUJIAN MEDICAL JOURNAL,2019,41(06):12-15.
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嬰幼兒反復(fù)喘息136例病因分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期數(shù):
2019年06期
頁(yè)碼:
12-15
欄目:
臨床研究
出版日期:
2019-12-25

文章信息/Info

Title:
Etiological analysis of recurrent wheezing in 136 infants
文章編號(hào):
1002-2600(2019)06-0012-04
作者:
陳瓊?cè)A 鄭敬陽(yáng) 張圳杰 林印濤 曾麗娥 林春燕 張 譚
福建省泉州市兒童醫(yī)院呼吸科(泉州 362000)
Author(s):
CHEN Qionghua; ZHENG Jingyang; ZHANG Zhenjie; LIN Yintao; ZENG Lie; LIN Chunyan; ZHANG Tan.
Department of Respiratory, Quanzhou Childrens Hospital, Quanzhou, Fujian 362000, China
關(guān)鍵詞:
嬰幼兒;  喘息;  病因
Keywords:
infant;  wheezing;  etiology
分類號(hào):
R725.6
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 分析嬰幼兒反復(fù)喘息的病因。方法 收集患兒的一般資料、臨床癥狀及體征、病原學(xué)、胸部CT 等影像學(xué)、免疫學(xué)進(jìn)行分析,研究反復(fù)喘息的病因。結(jié)果 引起反復(fù)喘息的主要原因?yàn)?嬰幼兒哮喘47例(34.6%)、感染62例(45.6%)、閉塞性細(xì)支氣管炎4例(2.9%)、支氣管肺發(fā)育不良7例(5.1%)、胃食管反流2例(1.5%),支氣管內(nèi)異物2例(1.5%),氣道畸形9例(6.6%),心血管畸形2例(1.5%),免疫缺陷1例(0.7%)。感染相關(guān)喘息中有23例被檢出合并現(xiàn)癥感染,支原體感染達(dá)16.1%。哮喘預(yù)測(cè)指數(shù)(API)陽(yáng)性者46例(34.6%)。106例胸部CT檢查中90例為炎癥改變,46例患兒支氣管鏡表現(xiàn)為氣管支氣管內(nèi)膜炎為主。62例患兒考慮感染后喘息,但還應(yīng)注意其他少見(jiàn)病因可能。結(jié)論 嬰幼兒反復(fù)喘息大部分有因可尋,感染相關(guān)喘息和哮喘是導(dǎo)致嬰幼兒反復(fù)喘息的常見(jiàn)原因,診斷應(yīng)從常見(jiàn)病入手,但還應(yīng)注意少見(jiàn)病可能,加強(qiáng)隨訪評(píng)估。
Abstract:
Objective To analyze the etiology of recurrent wheezing in infants.Methods The general information,clinical symptons and signs,etiology,chest CT and other imaging and immunology of the children were collected and analyzed to study the causes of recurrent wheezing.Results The main causes of recurrent wheezing were as follows: 47 infants with asthma(34.6%), 62 infants with infection(45.6%), 4 infants with bronchiolitis obliterans(2.9%), 7 infants with bronchopulmonary dysplasia(5.1%), 2 infants with gastroesophageal reflux(1.5%), 2 infants with intrabronchial foreign bodies(1.5%), 9 infants with airway malformation(6.6%), 2 infants with cardiovascular malformation(1.5%)and 1 case with immune deficiency(0.7%).Current infection was found in 23 cases of infection-related wheezing, with mycoplasma infection reaching 16.1%.Asthma predictive index(API)was positive in 46 cases(34.6%).Ninety cases demonstrated inflammation in the chest CT examination, while 46 cases showed endobronchitis under bronchoscopy.Post-infection wheezing was considered in 62 patients, while attention should be paid to the possibility of other rare causes.Conclusion The causes of recurrent wheezing infant can be found in most cases.Infection-related wheezing and asthma are common causes.Diagnosis should be started with common diseases,and the possibility of rare diseases cannot be ignored.Strengthened follow-up evaluation are needed.

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更新日期/Last Update: 2019-12-25