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[1]吳道明 朱 琳 林 蕓 張麗華 吳松松 林 寧.光散射成像預(yù)測乳腺浸潤性癌腋窩淋巴結(jié)轉(zhuǎn)移的作用[J].福建醫(yī)藥雜志,2019,41(05):16-19.
　WU Daoming,ZHU Lin,LIN Yun,et al.Assessing prediction of axillary lymph node status in invasive breast carcinoma by using diffuse optical tomography[J].FUJIAN MEDICAL JOURNAL,2019,41(05):16-19.
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光散射成像預(yù)測乳腺浸潤性癌腋窩淋巴結(jié)轉(zhuǎn)移的作用()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
41
期數(shù):
2019年05期
頁碼:
16-19
欄目:
臨床研究
出版日期:
2019-10-15

文章信息/Info

Title:
Assessing prediction of axillary lymph node status in invasive breast carcinoma by using diffuse optical tomography
文章編號:
1002-2600(2019)05-0016-04
作者:
吳道明 朱 琳1 林 蕓 張麗華 吳松松 林 寧
福建醫(yī)科大學(xué)省立臨床醫(yī)學(xué)院 福建省立醫(yī)院超聲科(福州 350001)
Author(s):
WU Daoming; ZHU Lin; LIN Yun; ZHANG Lihua; WU Songsong; LIN Ning
Department of Ultrasonography, Fujian Provincial Hospital,Provincial Clinical Medical College of Fujian Medical University,Fuzhou,Fujian 350001,China
關(guān)鍵詞:
超聲;  光散射成像系統(tǒng);  乳腺腫瘤;  淋巴結(jié)
Keywords:
ultrasound;  diffuse optical tomography;  breast tumor;  lymph node
分類號:
R445.1; R737.9
文獻(xiàn)標(biāo)志碼:
A
摘要:
目的 探討光散射成像系統(tǒng)在預(yù)測浸潤性乳腺癌腋窩淋巴結(jié)轉(zhuǎn)移中的作用。方法 病理確診為浸潤性乳腺癌的141例分為腋窩淋巴結(jié)轉(zhuǎn)移組和腋窩淋巴結(jié)未轉(zhuǎn)移組,評價(jià)術(shù)前超聲光散射檢查腫瘤的各參數(shù)(SDI,HBT,SO2)值的差異,通過ROC曲線獲得預(yù)測腋窩淋巴結(jié)轉(zhuǎn)移的閾值,分析超聲結(jié)合DOT 系統(tǒng)對提高腋窩淋巴結(jié)轉(zhuǎn)移診斷準(zhǔn)確性的意義。結(jié)果 141例浸潤性乳腺癌患者腋窩淋巴結(jié)轉(zhuǎn)移82例,未轉(zhuǎn)移59例,組間SDI、HBT值比較的差異有統(tǒng)計(jì)學(xué)意義(P=0.007,P=0.002,P<0.01),而患者年齡與SO2值組間比較差異無統(tǒng)計(jì)學(xué)意義(P=0.83,P=0.712)。ROC曲線得出SDI、HBT診斷閾值為211.00,212.50。超聲聯(lián)合SDI和超聲聯(lián)合HBT診斷腋窩淋巴結(jié)轉(zhuǎn)移的敏感性、特異性、準(zhǔn)確性、陽性預(yù)測值、陰性預(yù)測值、AUC分別為:92.68%、94.92%、93.61%、96.20%、90.32%、0.933和91.46%、94.91%、92.91%、96.15%、88.89%、0.925,優(yōu)于單獨(dú)使用超聲診斷的74.12%、89.83%、82.27%、91.30%、76.61%、0.825。結(jié)論 結(jié)合SDI和HBT值可幫助提高超聲診斷腋窩淋巴結(jié)轉(zhuǎn)移的準(zhǔn)確性。
Abstract:
Objective To investigate the value of diffused optical tomography(DOT)in predicting metastasis of axillary lymph of invasive breast cancer.Methods In total, 141 patients of invasive breast carcinoma were divided into two groups: lymph node-positive and lymph node-negative According to histology.The differences of DOT finding of SDI,HBT,and SO2 was compared between the two groups.Obtain cutoff count of diagnosing axillary metastasis through ROC analysis.Study the value ofultrasound combine with DOT in improving the diagnostic accuracy of axillary lymph node metastasis was analyzed.Results The patients of invasive breast cancer were divided into two groups:metastasis in 82 patients and none metastasis in 59 patients.There were significant differences in SDI,HBT and size between the two groups(P=0.007,P=0.002,P<0.01),and no significant differences in age and SO2(P=0.83,P=0.712).The ROC curve showed that diagnostic threshdds of SDI and HBT were 211.00 and 212.50 in diagnosing of axillary metastasis.The sensitivity,specificity, accuracy, positive predictive value, negative predictive value,AUC of ultrasound with SDI and ultrasound with HBT were 92.68%,94.92%,93.61%,96.20%,90.32%,0.933 and 91.46%,94.91%,92.91%,96.15%,88.89%,0.925,and significantly greater than those of ultrasound alone(74.12%,89.83%,82.27%,91.30%,76.61%,0.825).Conclusion Combining SDI and HBT values can improve the accuracy of ultrasound diagnosis of axillary lymph node metastasis.

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備注/Memo

備注/Memo:
基金項(xiàng)目:福建省衛(wèi)生計(jì)生委青年科研課題(2015-1-3) 1 通信作者,Email:[email protected]
更新日期/Last Update: 2019-10-15