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[1]周紅衛(wèi) 黃志儉.呼吸機(jī)相關(guān)性肺炎患者血漿內(nèi)毒素的診斷及預(yù)后分析[J].福建醫(yī)藥雜志,2018,40(06):41-43.
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呼吸機(jī)相關(guān)性肺炎患者血漿內(nèi)毒素的診斷及預(yù)后分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
40
期數(shù):
2018年06期
頁(yè)碼:
41-43
欄目:
臨床研究·
出版日期:
2018-11-29

文章信息/Info

文章編號(hào):
1002-2600(2018)06-0041-04
作者:
周紅衛(wèi) 黃志儉1
福建中醫(yī)藥大學(xué)附屬?gòu)B門市中醫(yī)院重癥醫(yī)學(xué)科(廈門 361009)
關(guān)鍵詞:
內(nèi)毒素 革蘭氏陰性菌 呼吸機(jī)相關(guān)性肺炎 診斷 預(yù)后
分類號(hào):
R563.1
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 探討血漿內(nèi)毒素的檢測(cè)在呼吸機(jī)相關(guān)性肺炎患者中的診斷價(jià)值及對(duì)其預(yù)后的評(píng)估作用。方法 選擇我院急診科ICU呼吸機(jī)相關(guān)性肺炎患者52例,根據(jù)內(nèi)毒素檢測(cè)結(jié)果,將其分為內(nèi)毒素檢測(cè)陽(yáng)性組29例(A組)組及內(nèi)毒素檢測(cè)陰性組23例(B組); 采用鱟試劑的顯色基質(zhì)法,檢測(cè)血漿內(nèi)毒素含量,以≥0.4 EU/mL為陽(yáng)性結(jié)果,分析比較兩組的臨床指標(biāo)。結(jié)果 A組合并真菌感染及肝功能不全患者的比率顯著高于B組(P<0.05); 兩組合并膿毒血癥、多臟器功能不全(MODS)、急性呼吸窘迫綜合征(ARDS)、彌漫性血管內(nèi)凝血(DIC)等指標(biāo)比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05); 兩組病死率比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論 血漿內(nèi)毒素檢測(cè)可能不是作為診斷革蘭氏陰性菌呼吸機(jī)相關(guān)性肺炎的有效診斷指標(biāo),對(duì)其預(yù)后評(píng)估無(wú)明顯作用。

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備注/Memo

備注/Memo:
基金項(xiàng)目:廈門市科技計(jì)劃項(xiàng)目(3502Z20139005)
更新日期/Last Update: 2018-11-29