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[1]陳 艷 劉 敏 何甦暉 吳秋梅 楊珉珉.產(chǎn)前超聲診斷胎兒右位主動(dòng)脈弓合并迷走左鎖骨下動(dòng)脈及染色 體核型分析[J].福建醫(yī)藥雜志,2018,40(06):23-24.
　CHEN Yan,LIU Min,HE Suhui,et al.Prenatal ultrasonographic diagnosis and chromosome karyotype for right aortic arch with aberrant left subclavian artery[J].FUJIAN MEDICAL JOURNAL,2018,40(06):23-24.
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產(chǎn)前超聲診斷胎兒右位主動(dòng)脈弓合并迷走左鎖骨下動(dòng)脈及染色 體核型分析()
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《福建醫(yī)藥雜志》[ISSN:1002-2600/CN:35-1071/R]

卷:
40
期數(shù):
2018年06期
頁(yè)碼:
23-24
欄目:
臨床研究
出版日期:
2018-11-29

文章信息/Info

Title:
Prenatal ultrasonographic diagnosis and chromosome karyotype for right aortic arch with aberrant left subclavian artery
文章編號(hào):
1002-2600(2018)06-0023-03
作者:
陳 艷 劉 敏1 何甦暉 吳秋梅 楊珉珉
福建省婦幼保健院超聲科(福州 350001)
Author(s):
CHEN Yan; LIU Min; HE Suhui; WU Qiumei; YANG Minmin.
DepartmenDepartment of Ultrasound, Fujian Provincial Maternity and Childrens Hospital, Fuzhou, Fujian 350001, Chinat of Ultrasound, Fujian Provincial Maternity and Childrens Hospital, Fuzhou, Fujian 350001, China
關(guān)鍵詞:
產(chǎn)前超聲;  胎兒;  右位主動(dòng)脈弓;  迷走左鎖骨下動(dòng)脈;  染色體核型
Keywords:
prenatal ultrasound;  fetus;  RAA-ALSA;  chromosome karyotype
分類(lèi)號(hào):
R445.1;R714.53
文獻(xiàn)標(biāo)志碼:
B
摘要:
目的 總結(jié)右位主動(dòng)脈弓合并迷走左鎖骨下動(dòng)脈(RAA-ALSA)的產(chǎn)前超聲特征及染色體核型結(jié)果。方法 回顧性分析我院產(chǎn)前超聲診斷為RAA-ALSA的28例胎兒資料,包括產(chǎn)前超聲、產(chǎn)后新生兒心臟彩超或尸解結(jié)果、染色體核型分析結(jié)果以及臨床隨訪情況。結(jié)果 28例產(chǎn)前診斷的RAA-ALSA均經(jīng)過(guò)出生后新生兒心臟彩超或引產(chǎn)后尸解證實(shí),其中僅1例為18-三體綜合征,其余27例染色體核型正常。該組病例中,21例為孤立性RAA-ALSA,均為左位動(dòng)脈導(dǎo)管、活產(chǎn),隨訪至今未出現(xiàn)呼吸窘迫、吞咽困難等氣管食管壓迫癥狀。其余7例為RAA-ALSA伴左位動(dòng)脈導(dǎo)管合并其他心內(nèi)外畸形,其中4例合并室間隔缺損、主動(dòng)脈騎跨、肺動(dòng)脈狹窄; 1例合并室間隔缺損、主動(dòng)脈騎跨及胎兒左側(cè)多囊性發(fā)育不良腎; 1例合并完全性大動(dòng)脈轉(zhuǎn)位; 1例合并過(guò)渡型心內(nèi)膜墊缺損、永存左上腔靜脈及胎兒唇腭裂畸形; 此7例孕婦及家屬選擇引產(chǎn)并同意尸解。結(jié)論 RAA-ALSA多為孤立性,染色體核型分析多無(wú)異常,預(yù)后較好; RAA-ALSA有典型超聲圖像特征,產(chǎn)前超聲能夠?qū)Υ艘约昂喜⒌钠渌巫鞒鲈\斷,從而為產(chǎn)前咨詢(xún)及預(yù)后的個(gè)體化評(píng)估提供依據(jù)。
Abstract:
Objective To explore the prenatal ultrasonographic features and chromosome karyotype for right aortic arch with aberrant left subclavian artery(RAA-ALSA).Methods Prenatal echocardiography,postnatal echocardiography or autopsy pathological data,chromosome karyotype results and outcome of fetal RAA-ALSA in 28 cases were analyzed retrospectively.Results The 28 cases were confirmed by postpartum echocardiography or autopsy pathology,including 27 cases with normal chromosome karyotype and one case with Trisomy 18.Twenty-one cases which were isolated type(1eft-sided ductus arteriosus)were live birth,and had no respiratory tract and esophageal compression symptoms such as respiratory distress and dysphagia so far.The rest seven cases were complicated type,including intracardiac and extracardiac anomaly as follows:1)Four cases with ventricular septal defect,aortic riding and pulmonary artery stenosis.2)One case with ventricular septal defect,aortic riding and fetal left polycystic dysplastic kidney.3)One case with transposition of great arteries. 4)One case with transitional endocardial cupshion defect,persistent left superior vena cava and fetal cleft lip and palate. All the seven cases were terminated. Conclusion RAA-ALSA is mostly isolated.Most of them have no abnormalities in chromosome karyotype analysis and have good prognosis. RAA-ALSA has characteristic ultrasound findings.Associated intracardiac and extracardiac anomaly can be accurately diagnosed by prenatal ultrasound,which can provide scientific basis for prenatal counseling and fetal prognosis assessment.

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更新日期/Last Update: 2018-11-29